Rapid synthesis of gold and silver nanoparticles using tryptone as a reducing and capping agent

Mehta, Sourabh; Sequeira, Marilyn P.; Muthurajana, Harries; D’Souza, Jacinta S.

doi:10.1007/s13204-018-0684-1

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…However, lack of colloidal stability, time-consuming synthesis procedures, cost, etc. pose major challenges in developing them for industrial and commercial applications [ 59 ]. Here, using tryptone as a stabilizing agent, we sought to mitigate the problems associated with colloidal stability, undesired toxicity, cost, time of their synthesis, and adverse effects on the ecosystem.…”

Section: Discussionmentioning

confidence: 99%

Tryptone-stabilized silver nanoparticles’ potential to mitigate planktonic and biofilm growth forms of Serratia marcescens

et al. 2022

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Several microbial pathogens are capable of forming biofilms. These microbial communities pose a serious challenge to the healthcare sector as they are quite difficult to combat. Given the challenges associated with the antibiotic-based management of biofilms, the research focus has now been shifted towards finding alternate treatment strategies that can replace or complement the antibacterial properties of antibiotics. The field of nanotechnology offers several novel and revolutionary approaches to eradicate biofilm-forming microbes. In this study, we evaluated the antibacterial and antibiofilm efficacy of in-house synthesized, tryptone-stabilized silver nanoparticles (Ts-AgNPs) against the superbug Serratia marcescens . The nanoparticles were of spherical morphology with an average hydrodynamic diameter of 170 nm and considerable colloidal stability with a Zeta potential of − 24 ± 6.15 mV. Ts-AgNPs showed strong antibacterial activities with a minimum inhibitory concentration (MIC 50 ) of 2.5 µg/mL and minimum bactericidal concentration (MBC) of 12.5 µg/mL against S. marcescens . The nanoparticles altered the cell surface hydrophobicity and inhibited biofilm formation. The Ts-AgNPs were also effective in distorting pre-existing biofilms by degrading the extracellular DNA (eDNA) component of the extracellular polymeric substance (EPS) layer. Furthermore, reduction in quorum-sensing (QS)-induced virulence factors produced by S. marcescens indicated that Ts-AgNPs attenuated the QS pathway. Together, these findings suggest that Ts-AgNPs are an important anti-planktonic and antibiofilm agent that can be explored for both the prevention and treatment of infections caused by S. marcescens . Graphical abstract Supplementary Information The online version contains supplementary material available at 10.1007/s00775-022-01977-w.

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Section: Discussionmentioning

confidence: 99%

Tryptone-stabilized silver nanoparticles’ potential to mitigate planktonic and biofilm growth forms of Serratia marcescens

et al. 2022

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“…The structure of AgNPs with organic deposits on the surface. [83] such as leakage and the ability to create antibacterial coatings on the surface of cells, bacteria, and viruses, effectively eliminating bacteria or controlling their growth. Some studies have reported that silver nanoparticles can significantly destroy certain bacteria (such as Gram-positive and Gram-negative bacteria) and viruses.…”

Section: Against Bacteria and Virusesmentioning

confidence: 99%

Silver Nanoparticles as Antiviral and Antibacterial Agents: A Comprehensive Review of Synthesis Methods and Therapeutic Application

Sabaghian

2024

ChemistrySelect

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Silver nanoparticles have shown inhibitory capabilities and its use in battling viral infections are strengthened by its potent antibacterial activity. Notably, since it directly affects antiviral efficacy, the proper choice of synthesis process for making silver nanoparticles is a vital element to be taken into consideration. The synthesis of silver nanoparticles for the treatment of viral and bacterial infections involves creating silver particles at the nanoscale with unique antimicrobial properties. Various methods exist for synthesizing silver nanoparticles, including chemical reduction, green synthesis, and physical methods. Chemical reduction involves using reducing agents to convert silver ions into silver nanoparticles. Green synthesis employs reducing agents in an environmentally friendly manner. Physical methods rely on techniques such as laser ablation or thermal evaporation to produce silver nanoparticles. In order to provide technological guidance for choosing antiviral silver nanoparticle manufacturing methods, this paper introduces and explores alternative synthesis methods for creating silver nanoparticles.

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Arginine and lysine-functionalized layered double hydroxides as efficient sorbents for radioactive Co2+ removal by chelate-facilitated immobilization

Koilraj

Kalusulingam

Sasaki

2019

Chemical Engineering Journal

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Rapid synthesis of gold and silver nanoparticles using tryptone as a reducing and capping agent

Cited by 5 publications

References 22 publications

Tryptone-stabilized silver nanoparticles’ potential to mitigate planktonic and biofilm growth forms of Serratia marcescens

Tryptone-stabilized silver nanoparticles’ potential to mitigate planktonic and biofilm growth forms of Serratia marcescens

Silver Nanoparticles as Antiviral and Antibacterial Agents: A Comprehensive Review of Synthesis Methods and Therapeutic Application

Arginine and lysine-functionalized layered double hydroxides as efficient sorbents for radioactive Co2+ removal by chelate-facilitated immobilization

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