Rapid selective colorimetric sensing of polyphosphates by ionic resorcinarene cavitand interdigitated gold nanoparticles

Skinner, Amanda V.; Han, Sangbum; Balasubramanian, Ramjee

doi:10.1016/j.snb.2017.03.097

Cited by 10 publications

(4 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A sensitive colorimetric-based nanosensor for the detection of pyrophosphate at μM concentrations (LOD, 140 nM) in 10 mM HEPES buffer, pH 7.4, was reported by Balasubramanian and co-workers (N13.3 in Figure 286). 1224 In this example, gold nanoparticles were decorated with positively charged resorcinarenes that served as recognition units for negatively charged pyrophosphate anions. Thus, in the Recently, Wu, Zhang, and coworkers reported a smartphone-based detection system for pyrophosphate (LOD, 1 μM) in water and in meat samples.…”

Section: Nanosensors For Phosphate and Pyrophosphate Anionsmentioning

confidence: 99%

See 1 more Smart Citation

Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids

et al. 2022

View full text Add to dashboard Cite

Synthetic molecular probes, chemosensors, and nanosensors used in combination with innovative assay protocols hold great potential for the development of robust, low-cost, and fast-responding sensors that are applicable in biofluids (urine, blood, and saliva). Particularly, the development of sensors for metabolites, neurotransmitters, drugs, and inorganic ions is highly desirable due to a lack of suitable biosensors. In addition, the monitoring and analysis of metabolic and signaling networks in cells and organisms by optical probes and chemosensors is becoming increasingly important in molecular biology and medicine. Thus, new perspectives for personalized diagnostics, theranostics, and biochemical/ medical research will be unlocked when standing limitations of artificial binders and receptors are overcome. In this review, we survey synthetic sensing systems that have promising (future) application potential for the detection of small molecules, cations, and anions in aqueous media and biofluids. Special attention was given to sensing systems that provide a readily measurable optical signal through dynamic covalent chemistry, supramolecular host− guest interactions, or nanoparticles featuring plasmonic effects. This review shall also enable the reader to evaluate the current performance of molecular probes, chemosensors, and nanosensors in terms of sensitivity and selectivity with respect to practical requirement, and thereby inspiring new ideas for the development of further advanced systems.

show abstract

Section: Nanosensors For Phosphate and Pyrophosphate Anionsmentioning

confidence: 99%

“…Resorcinarene-functionalized AuNPs ( N13.3 ) used for colorimetric detection of phosphates at μM concentrations in 10 mM HEPES buffer, pH 7.4. Adapted with permission from ref . Copyright 2017 Elsevier BV.…”

Section: Phosphatesmentioning

confidence: 99%

Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids

et al. 2022

View full text Add to dashboard Cite

show abstract

“…This is the reason why the skeleton of all cavitands also show high affinity to electron-poor aromatics. Therefore, sensing methods based on photoluminescence and electrochemical techniques have widespread application [ 7 , 8 , 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Anodic Polymerization of Phenylphenols in Methyl Isobutyl Ketone and Mesityl Oxide: Incorporation of a Cavitand into the Layers Formed for Sensing Phenols in Organic Media

Kiss

Nagymihály

Szabó³

et al. 2022

Molecules

View full text Add to dashboard Cite

The electropolymerization of three phenylphenol isomers was studied in methyl isobutyl ketone and mesityl oxide, and the remarkable differences highlighted the importance of the carbon–carbon double bond in mesityl oxide. In the case of each substrate, a brownish deposit formed during the electrooxidation. The obvious difference between the polymers formed from the two solvents was recognized via voltammetric signal enhancement of 4-methoxyphenol and 4-chlorophenol, and it was only observed in the case of mesityl oxide. The experiments highlighted that incorporation of a cavitand with biphenyl groups on the upper rim of the polymers of phenylphenols improved the results to a small extent. The cavitand was, itself, electroactive without any fouling effect. As 2-phenylphenol is by far the cheapest of the three isomers, a cavitand was incorporated into its polymer, which was exploited to solve analytical problems while mesityl oxide was used as solvent. Useful quantifications were achieved in organic solvents; however, it failed under aqueous conditions due to the high hydrophobicity of the deposit. Application of differential pulse voltammetry for 4-methoxyphenol and 4-chlorophenol gave detection limits of 9.28 and 50.8 μM in acetonitrile, respectively. This procedure resulted in the immobilization of cavitand derivatives onto the electrode’s surface, and the layer formed offered selective sensing of phenols by electrochemical methods.

show abstract

“…It should be noted that other strategies of detecting diphosphate anions by using immobilized receptors exist. Solutions of AuNPs containing tetracationic resorcinarene-derived cavitands were, for example, also shown to respond to the presence of diphosphate by a color change [27] due to the known diphosphate affinity of such cavitands [28]. Self-assembled monolayers on gold containing a bis(carbazolyl)urea-derived receptor allowed the sensitive detection of diphosphate in water by surface plasmon resonance (SPR) [29].…”

Section: Introductionmentioning

confidence: 99%

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

Reinke¹,

Bartl²,

Koch³

et al. 2020

Beilstein J. Org. Chem.

View full text Add to dashboard Cite

Gold nanoparticles covered with a mixture of ligands of which one type contains solubilizing triethylene glycol residues and the other peripheral zinc(II)–dipicolylamine (DPA) complexes allowed the optical detection of hydrogenphosphate, diphosphate, and triphosphate anions in water/methanol 1:2 (v/v). These anions caused the bright red solutions of the nanoparticles to change their color because of nanoparticle aggregation followed by precipitation, whereas halides or oxoanions such as sulfate, nitrate, or carbonate produced no effect. The sensitivity of phosphate sensing depended on the nature of the anion, with diphosphate and triphosphate inducing visual changes at significantly lower concentrations than hydrogenphosphate. In addition, the sensing sensitivity was also affected by the ratio of the ligands on the nanoparticle surface, decreasing as the number of immobilized zinc(II)–dipicolylamine groups increased. A nanoparticle containing a 9:1 ratio of the solubilizing and the anion-binding ligand showed a color change at diphosphate and triphosphate concentrations as low as 10 μmol/L, for example, and precipitated at slightly higher concentrations. Hydrogenphosphate induced a nanoparticle precipitation only at a concentration of ca. 400 μmol/L, at which the precipitates formed in the presence of diphosphates and triphosphates redissolved. A nanoparticle containing fewer binding sites was more sensitive, while increasing the relative number of zinc(II)–dipicolylamine complexes beyond 25% had a negative impact on the limit of detection and the optical response. Transmission electron microscopy provided evidence that the changes of the nanoparticle properties observed in the presence of the phosphates were due to a nanoparticle crosslinking, consistent with the preferred binding mode of zinc(II)–dipicolylamine complexes with phosphate anions which involves binding of the anion between two metal centers. This work thus provided information on how the behavior of mixed monolayer-protected gold nanoparticles is affected by multivalent interactions, at the same time introducing a method to assess whether certain biologically relevant anions are present in an aqueous solution within a specific concentration range.

show abstract

Rapid selective colorimetric sensing of polyphosphates by ionic resorcinarene cavitand interdigitated gold nanoparticles

Cited by 10 publications

References 58 publications

Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids

Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids

Anodic Polymerization of Phenylphenols in Methyl Isobutyl Ketone and Mesityl Oxide: Incorporation of a Cavitand into the Layers Formed for Sensing Phenols in Organic Media

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

Contact Info

Product

Resources

About