Rapid Response of Confluent Reticulated Papillomatosis to the Combination of Doxycycline and Topical Tretinoin: A Case Report

Abstract

Confluent reticulated papillomatosis(CRP) is a disease which is characterized with peripheral, reticular hyperpigmented patches and hyperkeratotic papules, first defined in 1927. The disease, also known as Gougerot Carteaud syndrome, mostly affects young women in 2nd and 3rd decade of life. Interscapular, epigastric and intermammary areas are involved in most of the cases. Although etiopathogenesis of the disease is still unclear, antibiotics such as minocycline, doxycycline, azithromycin and retinoic acid derivatives are being used in the treatment. Clearance of the lesion in CRP may take a long time. Herein, we present our case in order to emphasize rapid response to the combination therapy of systemic doxycycline and topical tretinoin.