Rapid Resolution of Chronic Back Pain with Magnesium Glycinate in a Pediatric Patient

Abstract

A 10-year-old male presented to a pediatric complex chronic pain clinic with debilitating back pain associated with vertebral compression fractures secondary to corticosteroid-induced osteoporosis. The pain failed to respond to routine analgesics and zoledronic acid. Oral magnesium glycinate and topical magnesium/guaifenesin cream were initiated upon presentation to the clinic, and resulted in a rapid and sustained reduction in pain, increased flexibility and improved quality of life. Magnesium is a known N-methyl-D-aspartate receptor antagonist, and should be considered in the management of chronic pain. The roles of glycine and guaifenesin in the management of chronic pain are not well-understood, but may warrant further examination in the context of chronic pain.