Rapid Prototyping Mandible Model for Dental Implant Surgery Simulation

Cheng, Yih‐Lin; Lin, Yen-Juei; Shih, Kan-Shan

doi:10.3722/cadaps.2012.177-185

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…A profile line was drawn from the peripheral host bone, across the defect area to the other side of the defect boundary. The gray values on the profile line were shown in a curve diagram, which were in proportional to the bone mineral density (in a scale from 0 to 255) [52]. The percentage of the increase of bone density in the scaffold comparing to host bone was calculated as: (gray value in scaffold - gray value in host bone)/gray value in host bone (technical replicates n = 6).…”

Section: Methodsmentioning

confidence: 99%

Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium

et al. 2015

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Human induced pluripotent stem cells (hiPSCs) are an exciting cell source with great potential for tissue engineering. Human bone marrow mesenchymal stem cells (hBMSCs) have been used in clinics but are limited by several disadvantages, hence alternative sources of MSCs such as umbilical cord MSCs (hUCMSCs) are being investigated. However, there has been no report comparing hiPSCs, hUCMSCs and hBMSCs for bone regeneration. The objectives of this pilot study were to investigate hiPSCs, hUCMSCs and hBMSCs for bone tissue engineering, and compare their bone regeneration via seeding on biofunctionalized macroporous calcium phosphate cement (CPC) in rat cranial defects. For all three types of cells, approximately 90% of the cells remained alive on CPC scaffolds. Osteogenic genes were up-regulated, and mineral synthesis by cells increased with time in vitro for all three types of cells. The new bone area fractions at 12 weeks (mean ± sd; n = 6) were (30.4 ± 5.8)%, (27.4 ± 9.7)% and (22.6 ± 4.7)% in hiPSC-MSC-CPC, hUCMSC-CPC and hBMSC-CPC respectively, compared to (11.0 ± 6.3)% for control (p < 0.05). No significant differences were detected among the three types of stem cells (p > 0.1). New blood vessel density was higher in cell-seeded groups than control (p < 0.05). De novo bone formation and participation by implanted cells was confirmed via immunohistochemical staining. In conclusion, (1) hiPSCs, hUCMSCs and hBMSCs greatly enhanced bone regeneration, more than doubling the new bone amount of cell-free CPC control; (2) hiPSC-MSCs and hUCMSCs represented viable alternatives to hBMSCs; (3) biofunctionalized macroporous CPC-stem cell constructs had a robust capacity for bone regeneration.

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Section: Methodsmentioning

confidence: 99%

Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium

et al. 2015

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“…Usually, such a process is called rapid prototyping (RP) since it can be performed at high speed. Stereolithography, 3D printing, fused deposition modelling (including inkjet printing and jetted photopolymer) and laminated object manufacturing are the representative RP manufacturing methods [4,5,6,7,8,9]. Recently, high performance RP machines are on the market from several companies [10].…”

Section: Introductionmentioning

confidence: 99%

A Double-Sided In-Plane Lateral Comb-Drive Actuator Fabricated by a Plaster-Based 3D-Printer

Mizuno

Takahashi

2015

KEM

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In this paper, design, fabrication and characterization of a double-sided in-plane lateral comb-drive actuator fabricated by a plaster-based 3D-printer is described. The design is based on MEMS (Micro Electro-mechanical Systems) design concept. The movable part of the actuator consists of a (10x52.5) mm rectangular plate, and the end sides have depression areas in order to fit a (0.5x21.3) mm beam-shaped hinges. In the remaining sides of the plate, 18 comb fingers (0.5x10) mm are set at each opposite side. The stationary part of the actuator consists of 17 comb fingers with the same dimension to that of the stationary ones, and they are set at both sides of a frame and interdigitated with the movable comb fingers on the same plane. The gap between the movable and stationary comb fingers is 1.0mm. The structure thickness is 1.5mm. Such a structure, which both sides are provided with an in-plane interdigitated comb fingers, is called double-sided in-plane lateral comb-drive actuator. This actuator has been fabricated by using a plaster-based 3D-printer. Since plaster composite is an electrical insulating material, the structure has been suitably masked and the upper and lateral surfaces have been metallized thereafter by Au ion sputtering for the actuator electrodes formation. The hybrid fusion of 3D-printing manufacturing technology and MEMS-based design concept has been recently proposed by the authors and named as SMEMS (Sub-milli Electro-mechanical Systems), since the smallest possible fabrication size is in the order of sub-millimeters. The advantage of SMEMS technology is the quick and easy fabrication of 3D structures from 3D-CAD data. Furthermore, SMEMS is completely environment-clean since any hazardous chemicals or gases are used. The actuator has been driven by differential voltages, where both sides are biased at a voltage of 100V, and a 200 Vpp and its 180°shifted sinusoidal voltages are applied at each side. The actuator laterally moved by 96.8μm (full width) at a resonance frequency of 72Hz, and the mechanical quality factor has been estimated to be about 10.

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3D Printing Review in Numerous Applications for Dentistry

Ansari

Sheikh

2022

J. Inst. Eng. India Ser. C

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Rapid Prototyping Mandible Model for Dental Implant Surgery Simulation

Cited by 4 publications

References 8 publications

Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium

Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium

A Double-Sided In-Plane Lateral Comb-Drive Actuator Fabricated by a Plaster-Based 3D-Printer

3D Printing Review in Numerous Applications for Dentistry

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