Rapid popliteal artery release sensu A.N. Kazantsev in acute thrombosis in patients with COVID-19

Казанцев, А. Н.; Chernykh, K. P.; Bagdavadze, G. Sh.; Заркуа, Н. Э.; Калинин, Е. Ю.; Artyukhov, S. V.; Чикин, А. Е.; Линец, Ю. П.

doi:10.15829/1560-4071-2021-4413

Cited by 17 publications

(20 citation statements)

References 13 publications

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“…Выбор в пользу аутовенозного кондуита был исключен ввиду наличия у пациента клиники стенокардии, требующей запланированное коронарное шунтирование, что соответствует современным протоколам реваскуляризации в условиях наличия мультифокального атеросклероза [5][6][7][8][9][10]. Среди же 91 (12,0%) тромбозов артерий нижних конечностей невакцинированных больных 48 (5,4%) развились в "чистых" артериях (без признаков атеросклероза), что демонстрирует основной фактор, предрасполагающий к данному состоянию -инфекционный эндотелиит, оптимальной схемы лечения которого на сегодняшний день до сих пор не разработано [1,2,11].…”

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“…Повторный тромбоз после успешно выполненной тромбэктомии в боль-шинстве случаев развивался в 1 сут. после операции, что могло быть связано с поражением дистального микроциркуляторного русла [1,2,11,12]. Таким образом, периферическое сопротивление приводило к стазу и нивелировало эффект от хирургического восстановления магистрального кровотока.…”

Section: Discussionunclassified

“…Новая коронавирусная инфекция (COVID-19) повлияла на все стороны медицины, создав отягощенный прогноз течения известных хронических заболеваний (сахарный диабет, хроническая обструктивная болезнь легких и т.д.) [1,2]. Первой и наиболее изученной в мировом масштабе вакциной для профилактики заражения COVID-19 стала вакцина "Спутник V" (Гам-КОВИД-Вак -комбинированная векторная вакцина).…”

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Thrombosis in unvaccinated and Gam-COVID-Vac-vaccinated patients with COVID-19

et al. 2022

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Aim. To analyze the incidence of thrombotic events in unvaccinated and GamCOVID-Vac-vaccinated patients with coronavirus disease 2019 (COVID-19).Material and methods. This prospective study included 316 patients (group 1) vaccinated with two doses of Sputnik V (Gam-COVID-Vac) hospitalized between November 20, 2020 and June 1, 2021 for COVID-19. Group 2 included 754 unvaccinated patients with a positive polymerase chain reaction test for SARSCoV-2.Results. During inhospital period, deaths were recorded only in unvaccinated patients (group 1 — 0%; group 2 — 10,7% (n=87); p<0,0001). Among unvaccinated patients, the following thrombotic events were more common: upper- extremity deep vein thrombosis (group 1 — 0,63% (n=2); group 2 — 5,4% (n=41); p=0,0003), lower-extremity deep vein thrombosis (group 1 — 2,21% (n=7); group 2 — 11,4% (n=86); p<0,0001), pulmonary embolism (PE) (group 1 — 0%; group 2 — 3,4% (n=26); p=0,0008), lower limb arterial thrombosis followed by thrombectomy (group 1 — 0,31% (n=1); group 2 — 12% (n=91); p <0,0001), lower limb arterial retrombosis after retrombectomy (group 1 — 0,31% (n=1); group 2 — 8,7% (n=66); p<0,0001), lower limb amputation (group 1 — 0%; group 2 — 8,7% (n=66); p<0,0001), composite endpoint (group 1 — 3,8% (n=12); group 2 — 55,2% (n=416); p<0,0001). In the long-term follow-up period (125,5±26,5 days), recurrent COVID-19 developed significantly more often in unvaccinated patients (group 1 — 0,63% (n=2); group 2 — 3,6% (n=24); p=0,007). All arterial and venous thromboses, limb amputations were diagnosed only among unvaccinated patients.Conclusion. Vaccination with Sputnik V (Gam-COVID-Vak) prevents the severe COVID-19 with the development of deaths, pulmonary embolism, venous and arterial thrombosis.

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Thrombosis in unvaccinated and Gam-COVID-Vac-vaccinated patients with COVID-19

et al. 2022

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“…It has been more than two years since the new coronavirus infection reached pandemic status. The clinical spectrum of this pathology varies from an asymptomatic form to a severe disease characterized by hypoxemic respiratory failure, community-acquired polysegmental pneumonia, septic shock, and systemic multiple organ failure [ 1 , 2 ]. COVID-19 is often accompanied by hypercoagulability, micro- and macrovascular thrombotic angiopathy [3] .…”

Section: Introductionmentioning

confidence: 99%

Carotid Enadrterectomy for Thrombosis of the Internal Carotid Artery in Patients With COVID-19

Karkayeva

Tritenko

Коротких

et al. 2023

Current Problems in Cardiology

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“…Если говорить о новом в сердечно-сосудистой хирургии, то с появлением новой коронавирусной инфекции изменилась привычная природа развития артериальных тромбозов [1][2][3]. Последние стали формироваться не только в атеросклеротически измененных артериях, но и в совершенно «чистых» сосудах [1][2][3][4]. Генез данного события стал заключаться в совокупности двух процессов: коагулопатия, эндотелиит.…”

Section: Introductionunclassified

Spontaneous Hematoma of the Right Large Lumbar Muscle, Hemorrhagic Vasculitis, Multiple Arterial Thrombosis in the Background of COVID-19

Казанцев

Zharova

Chernykh

et al. 2022

Neotložnaâ med. pomoŝʹ

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Patient A., 65 years old, male. He was admitted to the City Alexandrovskaya Hospital with complaints of fever within 5 days to 39.0°C, dry cough, shortness of breath during exertion, pain in the right ﬂ ank of the abdomen and right lumbar region for 7 days. Three days earlier, the patient had received a positive polymerase chain reaction test for the presence of SARS-CoV-2. Examination of the patient revealed a hemorrhagic rash on both legs. The patient was consulted by a dermatovenerologist, acute infectious hemorrhagic vasculitis, bullous form, was diagnosed.According to multispiral computed tomography with angiography (MSCT AG) of the abdominal organs: the psoas major muscle on the right was thickened, its structure was determined by the accumulation of the contents of hemorrhagic density with signs of partial lysis in the marginal zone, with a total size of 52x48x148 mm. No data available for aortic aneurysm / dissection. The patient denied the presence of injuries, taking anticoagulant drugs. The psoas major muscle hematoma was regarded as spontaneous hematoma against the background of coagulopathy caused by COVID-19.According to the MSCT data of the chest organs, it was visualized: polysegmental lesion in both lungs, numerous areas of compaction of the lung tissue were determined by the type of ground glass, with zones of consolidation and reticular changes in the structure. The degree of damage to the lung tissue was 55%.In view of the fact that the patient had data for the presence of a hematoma of the psoas major muscle on the right, as well as hemorrhagic vasculitis, anticoagulant therapy was contraindicated. Laboratory tests revealed an increase in the level of procalcitonin up to 12.8 ng/ml, C-reactive protein up to 135.1 mg/l, leukocytes up to 13.46 10^9/l, ferritin up to 532.2 ng/ml, D-dimer up to 1145 ng/ml. A multidisciplinary council (infectious disease specialist, general surgeon, therapist, pulmonologist, vascular surgeon, dermatovenerologist, septologist) decided to revise and drain the hematoma of the psoas major muscle on the right, as a likely source of sepsis (increased procalcitonin). Under intravenous anesthesia, the hematoma was opened posteriorly peritoneally, evacuated (about 300 ml in volume), 2 drains were installed. On the 10th day after the operation, a control MSCT was performed, according to which the hematoma of the right psoas muscle decreased in size by half. A decision was made to remove the drains.On the 13th day after admission to the hospital, the patient developed pain in the right forearm, hand, left leg and foot. Performed MSCT revealed hypertension of the arteries of the upper extremities and arteries of the lower extremities: thrombosis of the distal third of the brachial, ulnar and radial arteries; thrombosis of the superﬁ cial femoral artery (PFA) on the left. An anticoagulant therapy was started (heparin 7500 IU intravenously in a stream with subsequent transfer to continuous intravenous administration using an infusion pump with an initial rate of 1000 IU per hour, under the control of APTT with an indicator reaching 1.5–2.5 times higher than the norm), disaggregant therapy (acetylsalicylic acid 100 mg once a day), analgesic therapy (ketorol 1.0 ml/m). An emergency simultaneous operation was performed: thrombectomy from the brachial, radial, and ulnar arteries on the right under local anesthesia (transverse arteriotomy of the brachial artery, Fogarty catheters 3F, 5F) with satisfactory antegrade and retrograde blood ﬂ ow; plus under spinal anesthesia, an attempt was made to thrombectomy, Fogarty 5 catheter passed freely, a weak retrograde blood ﬂ ow was obtained, but after 3 minutes, repeated thrombosis of the PBA developed). That followed by femoral-popliteal prosthetics (above the knee joint gap) with a synthetic prosthesis “Ekoﬂ on” with obtaining a satisfactory pulsation distally.On the 21st day after the operation, the patient was discharged from the institution in a satisfactory condition.

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Rapid popliteal artery release sensu A.N. Kazantsev in acute thrombosis in patients with COVID-19

Cited by 17 publications

References 13 publications

Thrombosis in unvaccinated and Gam-COVID-Vac-vaccinated patients with COVID-19

Thrombosis in unvaccinated and Gam-COVID-Vac-vaccinated patients with COVID-19

Carotid Enadrterectomy for Thrombosis of the Internal Carotid Artery in Patients With COVID-19

Spontaneous Hematoma of the Right Large Lumbar Muscle, Hemorrhagic Vasculitis, Multiple Arterial Thrombosis in the Background of COVID-19

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