Rapid One-Pot Multicomponent Dioxane-HCl Complex Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidine-2-One Derivatives

Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines

“…The key benefits of this procedure are the quick and easy workup process, the lack of solvents, the atom economy, the low cost, the great product yield, the superior atom economy, the lack of heating or refluxing, and the use of the dioxane–HCl complex as a catalyst. [ 39 ]…”

Carbazole-based photocatalyst (4CzIPN) for novel donor–acceptor (D–A) fluorophore-catalyzed visible-light-induced photosynthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thionesviaa proton-coupled electron transfer (PCET) process

“…3,4-Dihydropyrimidin-2-(1 H )-ones/thiones can be produced synthetically using a variety of catalysts, including Na 2 eosin Y, 22 copper( ii )-sulfamate, 23 bakers, yeast, 24 hydrotalcite, 25 hexaaquaaluminium( iii ) tetrafluoroborate, 26 TBAB, 27 copper( ii ) tetrafluoroborate, 28 , [Btto][ p -TSA], 29 triethylammonium acetate, 30 saccharin, 31 caffeine, 32 zirconium( iv )-salophen perfluorooctanesulfonate, 33 H 3 [PW 12 O 40 ], 34 dioxane-HCl, 35 WSi/A15, 36 H 4 [W 12 SiO 40 ], 37 Zr(H 2 PO 4 ) 2 , 38 and GO-chitosan. 39 Due to the lack of metal catalysts, expensive reagents, challenging reactions, and low yields, reaction times are prolonged, which has an influence on waste management.…”

Recyclable photocatalyst perovskite as a single-electron redox mediator for visible-light-driven photocatalysis gram-scale synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones in air atmosphere

“…A multitude of catalysts may be implemented in the synthetic production of 3,4-dihydropyrimidin-2-(1 H )-ones/thiones, including Cu/Cu 2 O@g-C 3 N 4 19 , N -(phenylsulfonyl)benzene sulfonamide 20 , h -BN/Fe 3 O 4 /Co 21 , Na 2 eosin Y 22 , copper(II)sulfamate 23 , bakers, yeast 24 , hydrotalcite 25 , hexaaquaaluminium (III) tetrafluoroborate 26 , TBAB 27 , copper (II) tetrafluoroborate 28 , [Btto][ p -TSA] 29 , triethylammonium acetate 30 , saccharin 31 , caffeine 32 , zirconium(IV)-salophen perfluorooctanesulfonate 33 , H 3 [PW 12 O 40 ] 34 , Dioxane-HCl 35 , 4CzIPN 36 , H 4 [W 12 SiO 40 ] 37 , Zr(H 2 PO 4 ) 2 38 , GO-chitosan 39 , and sodium dodecyl sulfate 40 . The prolonged reaction times, the exorbitant cost of reagents, tumultuous reaction mechanisms, and minimal product yields, foray into waste management concerns.…”