Rapid on-site evaluation (ROSE) with EUS-FNA: The ROSE Slooks beautiful

Liu, Enshuo; Sun, Siyu

doi:10.4103/eus.eus_65_19

Cited by 28 publications

(15 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mahmoudi et al (2008) completed a crosssectional study on 199 cytological brush samples and showed 77 patients (41%) with positive results for malignancy (25). Result-related variables included age, (13). In our study, ROSE was performed in 25% of cases and augmented the sensitivity of cytology to 80%.…”

Section: Discussionmentioning

confidence: 69%

“…The risk of the complications of malignancy is lower than the percutaneous method (12). In 20% of cases, this technique may lead to uncertain and suspicious results due to technical or tissue issues (13). Diagnostic accuracy has increased using a new generation of needles and ultrasound devices along with immunological and molecular diagnostic methods (14).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Investigation on the Results of Cytopathologic Tests of Pancreatobiliary System Performed in the Pathology Department in Iran

et al. 2021

View full text Add to dashboard Cite

Scan to discover onlineBackground & Objective: Pancreatobiliary system disorders commonly include inflammatory diseases and tumors. Diagnosis of pancreatic cancer is challenging and is mostly achieved when the disease has extensively progressed, and metastasis has occurred. Therefore, this study was performed to evaluate cytopathology in the diagnosis of Pancreatobiliary malignancies, which can improve diagnostic adequacy and accuracy.Methods: A total of 116 cytopathologic results of the Pancreatobiliary system, performed in the Pathology Department of Taleghani Hospital, Tehran, Iran during 2017-2018 were selected and examined in this observational study. The frequency of different results was determined and compared with other variables. Results:The most common location of the lesions was the pancreas (47%). The lesions were categorized as malignant, benign, negative, suspicious for malignancy (SFM), and atypical in 28%, 10%, 24%, 14%, and 9% of the cases, respectively. In other cases, lesions were considered non-diagnostic. Rapid on-site evaluation (ROSE) was conducted in 25% of patients. Compatibility of the initial and final diagnoses was 100%, 50%, and 60% in cases with "malignant", "benign", and "negative" diagnoses, respectively. The sensitivity, specificity, as well as positive and negative predictive values of cytopathology in the diagnosis of Pancreatobiliary lesions were 75.8%, 92.3%, 95.9%, and 61.5%, respectively. Conclusion:Our findings indicated that half of the lesions of the Pancreatobiliary system were positive, SFM, and atypical. Fine-needle aspiration (FNA) and endoscopic ultrasoundguided FNA (EUS-FNA) were effective modalities in diagnosing Pancreatobiliary malignancies. The most important point in our experience is the increase in diagnostic sensitivity in the presence of ROSE. Therefore, the simultaneous use of ROSE and EUS-FNA can reduce the need for re-sampling.

show abstract

Section: Discussionmentioning

confidence: 69%

Section: Introductionmentioning

confidence: 99%

An Investigation on the Results of Cytopathologic Tests of Pancreatobiliary System Performed in the Pathology Department in Iran

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Rapid on-site evaluation (ROSE), which is intended to provide the real-time evaluation of sample adequacy and diagnostic yield, remains one of the most controversial topics in the field of EUS-FNA [ 27 ]. Currently, EUS-FNA with ROSE is mainly applied in pancreatic lesions.…”

Section: Discussionmentioning

confidence: 99%

“…In 12 cases with malignant esophageal strictures, ROSE depicted cancer cells in 11 cases, which demonstrated the potential application of ROSE as a supplementary method. While EUS-FNA, combined with ROSE, demonstrated non-inferior performance compared to EUS-FNA without ROSE, the major obstacles to the wide application of ROSE include limiting pathologist staffing, and a longer procedures time [ 27 ]. It should be addressed that in patient 11, even though both cytological and histological studies reported suspicious round tumor cells, with little cytoplasm, while no malignant cell was reported by ROSE, the final diagnosis was an esophageal glomus tumor, which is an extremely rare esophageal neoplasm [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Role of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) in the Diagnosis of Suspicious Malignant Esophageal Strictures

Liang

Qing

Chu

et al. 2023

JCM

View full text Add to dashboard Cite

(1) Background: The accurate diagnosis of esophageal strictures is quite critical for optimizing medical intervention. However, the diagnosis of suspicious malignant esophageal strictures with intact mucosa appearance and negative biopsy results is challenging. This study aimed to evaluate the role of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the diagnosis of suspicious esophageal strictures. (2) Methods: We retrospectively analyzed the cases with suspicious malignant esophageal strictures that underwent EUS-FNA, with or without rapid on-site evaluation (ROSE), in our hospital from April 2017 to September 2022. Their clinical manifestations, imaging examinations, gastroscopic examinations, EUS-FNA results, and therapeutic strategies were retrospectively recorded and analyzed. (3) Results: A total of 23 patients (15 male and 8 female) were enrolled in this study. Based on EUS-FNA results, 18 patients were diagnosed with malignancies, including 16 cases of primary esophageal cancer (13 squamous carcinomas and 3 adenocarcinomas), 1 case of mediastinal cancer, and 1 case of metastatic esophageal cancer; 1 case of tuberculosis was also confirmed by EUS-FNA. Among 4 cases of ambiguous diagnosis with EUS-FNA, 1 was diagnosed with an esophageal glomus tumor after surgical removal, and 2 patients survived for several years without medical intervention, which hinted at the possibility of benign esophageal strictures. No major complications, including bleeding or perforation, were observed. (4) Conclusions: EUS-FNA may serve as a safe and effective diagnostic tool in suspicious malignant esophageal strictures with accurate specimen acquisition, especially for biopsy-negative cases.

show abstract

“… 15–17 Some reports have shown that ROSE can improve diagnostic accuracy rates and reduce the number of needle passes during EUS-FNA. 18–20 However, ROSE is time-consuming, costly, and unapplicable in many hospitals due to a lack of pathologists. Currently, puncture needle selection remains the main focus of many researchers.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Endoscopic Ultrasound-Guided Fine Needle Aspiration with 19-Gauge and 22-Gauge Needles for Solid Pancreatic Lesions

Li¹,

Mi²,

Gao³

et al. 2021

IJGM

View full text Add to dashboard Cite

Purpose We aimed to compare the histological and/or cytological diagnostic outcomes of EUS-FNA using 19G and 22G needles for solid pancreatic lesions and to evaluate the feasibility and safety of 19G needle. Patients and Methods Data from patients with solid pancreatic lesions, who underwent EUS-FNA, were retrospectively retrieved from a single tertiary center from June 2017 to January 2021. The sensitivity, specificity, and accuracy of diagnosis, sample adequacy, number and time of punctures, and adverse events, were compared between the 19G and 22G groups. Univariate and multivariate logistic regression analyses were used to identify optimal factors for a correct histological diagnosis. Results A total of 186 patients (19G group, n = 90; 22G group, n = 96) were analyzed in the study. The higher sensitivity and accuracy were observed in 19G group than those in the 22G group both in histological evaluation (89.3% vs 76%, p = 0.031; 91.1% vs 79.2%, p = 0.023; respectively) and in the combined histological and cytological evaluations (93.3% vs 81.3%, p = 0.027; 94.4% vs 84.3%, p = 0.027, respectively). However, there were no significant differences in specificity, positive predictive value (PPV), and negative predictive value (NPV). The number of needle passes and the puncture time were significantly lower in the 19G group than that in the 22G group (1.66 ± 0.07 vs 2.25 ± 0.08, p < 0.001; 125.4 ± 4.93s vs 169.0 ± 5.6s p < 0.001; respectively). Only 2 cases were failed in the 19G group and no serious complications occurred. Univariate and multivariate logistic analyses suggested that CA199 levels and needle types are related to the accuracy of the EUS-FNA histological diagnosis. Conclusion EUS-FNA using a 19G needle is effective and safe for solid pancreatic lesions. Compared with the 22G needle, EUS-FNA with a 19G needle can obtain a better histological diagnostic accuracy of solid pancreatic lesions, and with fewer needle passes and in a shorter time.

show abstract

Rapid on-site evaluation (ROSE) with EUS-FNA: The ROSE Slooks beautiful

Cited by 28 publications

References 40 publications

An Investigation on the Results of Cytopathologic Tests of Pancreatobiliary System Performed in the Pathology Department in Iran

An Investigation on the Results of Cytopathologic Tests of Pancreatobiliary System Performed in the Pathology Department in Iran

Role of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) in the Diagnosis of Suspicious Malignant Esophageal Strictures

Comparison of Endoscopic Ultrasound-Guided Fine Needle Aspiration with 19-Gauge and 22-Gauge Needles for Solid Pancreatic Lesions

Contact Info

Product

Resources

About