Rapid on-site evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of hilar and mediastinal lymphadenopathy in patients with lung cancer

Guo, Hongbo; Liu, Sujing; Guo, Jun; Li, Bobo; Li, Wanhu; Lu, Zuo-wei; Sun, Jian; Zhang, Baijiang; Yu, Jinming

doi:10.1016/j.canlet.2015.11.038

Cited by 47 publications

(32 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, we observed an increase in number of punctures per site of lymph node during the study, notably after starting using ROSE. This is in contrast to a recent report of less number of punctures needed when ROSE is used . We think both the introduction of ROSE and the increased experience among the endoscopy team may account for this results.…”

Section: Discussioncontrasting

confidence: 85%

Learning endobronchial ultrasound transbronchial needle aspiration – a 6‐year experience at a single institution

Sørhaug

Hjelde

Hatlen

et al. 2016

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 85%

Learning endobronchial ultrasound transbronchial needle aspiration – a 6‐year experience at a single institution

Sørhaug

Hjelde

Hatlen

et al. 2016

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

“…To our knowledge, a positive impact of ROSE on accuracy in this setting was only observed in one retrospective univariate analysis of 236 patients with suspected lung cancer [17]. A lack of power could explain the overall difficulty in showing a significant impact of ROSE on accuracy and, indeed, the relatively good diagnostic yield of EBUS-TBNA contributes to this lack of power.…”

Section: Discussionmentioning

confidence: 99%

“…In 2 retrospective studies, ROSE did not improve the diagnostic yield of EBUS-TBNA [15, 16], but one of the studies reported an improvement of the adequacy of the sampled material [16]. In a recent retrospective trial, ROSE was shown to enhance the diagnostic yield [17]. A first randomized controlled trial failed to show an increased yield with ROSE in EBUS-TBNA, but was underpowered [18].…”

Section: Introductionmentioning

confidence: 99%

Utility of Rapid On-Site Cytologic Evaluation during Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Malignant and Nonmalignant Disease

Gianella¹,

Soccal²,

Plojoux³

et al. 2018

Acta Cytologica

View full text Add to dashboard Cite

Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an accurate procedure to sample mediastinal tissue. Rapid on-site cytologic evaluation (ROSE) has been advocated to improve the performance of this procedure, but its benefit remains controversial. Our objective is to assess the utility of ROSE for EBUS-TBNA diagnostic accuracy among unselected patients. Methods: We prospectively collected data from all consecutive EBUS-TBNA procedures performed between 2008 and 2014. ROSE was introduced since 2011 in our daily practice. The accuracy of EBUS-TBNA with and without ROSE was compared in a univariate and multivariate model accounting for confounding factors. The impact of ROSE was then analyzed according to the etiology and size of the lesions. Results: Among 348 EBUS-TBNA procedures analyzed, 213 were performed with ROSE. The overall accuracy tended to be better with ROSE than without (90.6 vs. 84.4%; p = 0.082). After adjustment in a multivariate model, the benefit of ROSE still did not reach statistical significance (adjusted odds ratio 1.86; 95% confidence interval 0.79–4.41). Similar results were obtained in subgroups of patients with malignant disease or sarcoidosis. The size of the lesion did not influence the impact of ROSE on accuracy. Conclusions: ROSE was associated with a moderate increase in the accuracy of EBUS-TBNA, but the difference was not statistically significant. The same effect of ROSE was observed in malignant and nonmalignant lesions and this effect was not influenced by the lesion’s size.

show abstract

“…Moreover, ROSE reduces turnaround time (ie, the amount of time taken to give a diagnosis) as no time is wasted looking for the more appropriate complementary test to take. Concordance between ROSE diagnosis and final diagnoses was found to be up to 98% …”

Section: Rapid On‐site Evaluation (Rose)mentioning

confidence: 99%

Management of thyroid cytological material, preanalytical procedures and bio‐banking

et al. 2018

View full text Add to dashboard Cite

Thyroid nodules are common and are increasingly detected due to recent advances in imaging techniques. However, clinically relevant thyroid cancer is rare and the mortality from aggressive thyroid cancer remains constant. Fine needle aspiration cytology (FNAC) is a standard method for diagnosing thyroid malignancy and the discrimination of malignant nodules from goitre. As the examined nodules on thyroid FNAC are often small incidental findings, it is important to maintain a low rate of undetermined diagnoses requiring further clinical work up or surgery. The most important factors determining the accuracy of the cytological diagnosis and suitability for biobanking of thyroid FNACs are the quality of the sample and availability of adequate tissue for auxiliary studies. This article discusses technical aspects (preanalytics) of performing thyroid FNAC, including image guidance and rapid on-site evaluation, sample collection methods (conventional slides, liquid-based methods, cell blocks) and storage (bio-banking). The spectrum of special studies (immunocytochemistry on direct slides or liquid-based cytology, immunohistochemistry on cell blocks and molecular methods) required for improving the precision of the cytological diagnosis of the thyroid nodules is also discussed.

show abstract

Rapid on-site evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of hilar and mediastinal lymphadenopathy in patients with lung cancer

Cited by 47 publications

References 25 publications

Learning endobronchial ultrasound transbronchial needle aspiration – a 6‐year experience at a single institution

Learning endobronchial ultrasound transbronchial needle aspiration – a 6‐year experience at a single institution

Utility of Rapid On-Site Cytologic Evaluation during Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Malignant and Nonmalignant Disease

Management of thyroid cytological material, preanalytical procedures and bio‐banking

Contact Info

Product

Resources

About