Rapid non-target screening of organic pollutants in water by ultraperformance liquid chromatography coupled to time-of-light mass spectrometry

Ibáñez, María; Sancho, Juan V.; Hernández, Félix; McMillan, Daniel; Rao, Ramesh

doi:10.1016/j.trac.2008.03.007

Cited by 182 publications

(106 citation statements)

References 33 publications

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“…Hyphenation of UPLC with TOF-MS is very attractive due to the improved analytical characteristics resulting from both techniques. However, only a few examples of applications of this technique can be found in the literature, due to the very recent introduction of this instrumentation in research laboratories [18,19].…”

Section: Introductionmentioning

confidence: 99%

Fast determination of toxic diethylene glycol in toothpaste by ultra-performance liquid chromatography–time of flight mass spectrometry

2008

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A rapid method for determining diethylene glycol (DEG) in toothpaste based on the use of ultraperformance liquid chromatography (UPLC) coupled to time-of-flight mass spectrometry (TOF-MS) has been developed. The method has been validated in toothpaste samples spiked at different levels, 0.005, 0.1 and 5%, obtaining satisfactory recoveries (74-98%) and relative standard deviations (<4%). Quantification was carried out by using matrix-matched standards calibration. The developed method was applied to several types of toothpaste, making identification and quantification of DEG and other polyethylene glycols (PEG) feasible with very little sample manipulation, as only extraction with water is required. The excellent sensitivity of TOF-MS analysis performed in fullscan acquisition mode allowed the determination of DEG at concentration levels as low as 0.005% in samples and its reliable identification via the mass accuracy measurements provided by this instrument (<5 ppm).

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Section: Introductionmentioning

confidence: 99%

Fast determination of toxic diethylene glycol in toothpaste by ultra-performance liquid chromatography–time of flight mass spectrometry

2008

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“…The most employed methods for Imazalil determination are based on separation techniques such as HPLC coupled to mass detection [3][4][5] or UV detection [6][7][8].…”

Section: Imazalil ((Rsmentioning

confidence: 99%

Section: Imazalil ((Rsmentioning

confidence: 99%

“…In this sense, only three references [4,11,12] have been found in which Imazalil was studied in water samples. The first reference [4] is a very sensitive method for screening a wide range of organic pollutants in water samples, but no quantification results were described. The second one [11] describes the bioautograph technique for multiresidue determination of fungicide residues in plants and water, but Imazalil has only been studied in crop samples.…”

Section: Imazalil ((Rsmentioning

confidence: 99%

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Flow injection photoinduced chemiluminescence determination of imazalil in water samples

2010

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“…TOF MS gives a notable amount of chemical information in a single analysis that allows searching for a high number of compounds after MS acquisition. Our own research group has recently reported several applications of both GC-TOF and LC-TOF for investigation of organic contaminants in water samples [23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Analytical strategy based on the use of liquid chromatography and gas chromatography with triple-quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater

et al. 2010

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The presence of a wide variety of organic pollutants with different physico-chemical characteristics has been investigated in wastewater samples from a municipal solid waste treatment plant placed at Castellón, Spain. An advanced analytical strategy has been applied, consisting on the combined used of two powerful and complementary techniques, GC and LC, both hyphenated with tandem mass spectrometry with triple quadrupole analyzers. The GC-MS/MS method was based on sample extraction using The most commonly detected pollutants were herbicides (simazine, terbuthylazine, terbutryn, terbumeton, terbacil and diuron), together with fungicides (thiabendazole and carbendazim) and 4-t-octylphenol. In the light of data obtained, it has been proven that reverse osmosis process used for water treatment was efficient and notably reduced the levels of organic contaminants found in raw leachate samples. 3In order to investigate the presence of other non-target contaminants, water samples were also analyzed by using GC-TOF MS and LC-QTOF MS. Several organic pollutants that did not form a part of the previous list of target contaminants were identified in the samples, thanks to the good sensitivity of TOF MS in full spectrum acquisition mode and the valuable accurate mass information provided by these instruments. The insecticide diazinon, the fungicide diphenylamide, the UV filter benzophenone, N-butyl benzenesulfonamide (N-BBSA), the insect repellent diethyltoluamide, caffeine or pharmaceuticals like erythromycin, benzenesulfonanilide, ibruprofen, atenolol or paracetamol, were some of the compounds identified in the water samples analyzed.

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Rapid non-target screening of organic pollutants in water by ultraperformance liquid chromatography coupled to time-of-light mass spectrometry

Cited by 182 publications

References 33 publications

Fast determination of toxic diethylene glycol in toothpaste by ultra-performance liquid chromatography–time of flight mass spectrometry

Fast determination of toxic diethylene glycol in toothpaste by ultra-performance liquid chromatography–time of flight mass spectrometry

Flow injection photoinduced chemiluminescence determination of imazalil in water samples

Analytical strategy based on the use of liquid chromatography and gas chromatography with triple-quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater

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