Rapid Microscopic Spectral Imaging of Lung Cancer Tissue Based on Acousto-Optic Tunable Filter

Jiangwei, 原江伟 Yuan; Chunguang, 张春光 Zhang; Hao, 王号 Wang; Lei, 石磊 Shi

doi:10.3788/cjl201845.0407003

Cited by 2 publications

(4 citation statements)

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“…n o n e √ n o 2 sin 2 θ e 2 +n e 2 cos 2 θ e 2 (7) with markers o and e to distinguish o and e light. n o and n e are the principal refractive indices, respectively.…”

Section: Optimization Strategy For Polarization Multiplexing Applicat...mentioning

confidence: 99%

“…Now we can obtain θ o 2 and θ e 2 in the wave vector diagram (Figure 6f) at the incident angle of θ 0 , and n o 1 and n e 1 can also be obtained from Equation (7). The incident optical wave vectors can be solved by:…”

Section: Optimization Strategy For Polarization Multiplexing Applicat...mentioning

confidence: 99%

“…By switching the radio frequency (RF) signals applied to the transducer, the AOTF device can scan the spectral regions of interest [ 3 ]. The AOTF device offers fast response time, high spectral resolution, and wavelength configurability, making it an ideal choice for various applications, including remote sensing and medical imaging [ 4 , 5 , 6 , 7 , 8 ]. However, the low throughput limits the performance of the AOTF spectral imaging system [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

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Polarization-Multiplexed High-Throughput AOTF-Based Spectral Imaging System

Zhang,

Zhao,

Guo

et al. 2023

Materials

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Spectral imaging detection using acousto-optical tunable filters (AOTFs) faces a significant challenge of low throughput due to the traditional design that only receives a single polarization light. To overcome this issue, we propose a novel polarization multiplexing design and eliminate the need for crossed polarizers in the system. Our design allows for simultaneous collection of ±1 order light from the AOTF device, resulting in a more than two-fold increase in system throughput. Our analysis and experimental results validate the effectiveness of our design in improving system throughput and enhancing the imaging signal-to-noise ratio (SNR) by approximately 8 dB. In addition, AOTF devices used in polarization multiplexing applications require optimized crystal geometry parameter design that does not follow the parallel tangent principle. This paper proposes an optimization strategy for arbitrary AOTF devices which can achieve similar spectral effects. The implications of this work are significant for target detection applications.

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“…n o n e √ n o 2 sin 2 θ e 2 +n e 2 cos 2 θ e 2 (7) with markers o and e to distinguish o and e light. n o and n e are the principal refractive indices, respectively.…”

Section: Optimization Strategy For Polarization Multiplexing Applicat...mentioning

confidence: 99%

Section: Optimization Strategy For Polarization Multiplexing Applicat...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Polarization-Multiplexed High-Throughput AOTF-Based Spectral Imaging System

Zhang,

Zhao,

Guo

et al. 2023

Materials

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show abstract

“…Acousto-optic Tunable Filter (AOTF) is a fifth-generation electro-optic modulation spectroscopic device, it allows the AOTF-based imaging spectrometer for reducing volume, mass, and complexity, improving wavelength scanning speed and environmental adaptability of the instrumentation [1][2] [3] . At present, the AOTF imaging spectrometer is applied to many fields, such as atmospheric monitoring [4] , food and drug safety [5] , and in particular on deep space [6] .…”

Section: Introductionmentioning

confidence: 99%