Rapid method to study the sedimentation of a pigment suspension prepared for coating fluids

Bajdik, János; Bölcskei, Éva; Kelemen, András; Pintye‐Hódi, Klára

doi:10.1016/j.jpba.2007.04.003

Cited by 3 publications

(3 citation statements)

References 13 publications

(11 reference statements)

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“…Film coating fluids commonly contain a pigment suspension that can cause sedimentation of insoluble particles during the formation of the coating fluid. Bajdik et al 314 used EDXRF for the rapid measurement of sediments of TiO 2 in aqueous suspensions. The process factors evaluated were the stirring rate, time and volume to enable the authors to identify critical control points during the coating process.…”

Section: Thin Films and Coatingsmentioning

confidence: 99%

Atomic spectrometry update. X-ray fluorescence spectrometry

West

Ellis²,

Kregsamer

et al. 2008

J. Anal. At. Spectrom.

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This annual review of X-ray fluorescence covers developments over the period 2007-2008 in instrumentation and detectors, matrix correction and spectrum analysis procedures, X-ray optics and micro-fluorescence, synchrotron XRF, TXRF, portable XRF and on-line applications as assessed from the published literature. The trend set in previous years continues with an increase in the number of papers published on applications for XRF, including sample preparation, geological, environmental, archaeological, forensic, biological, clinical, thin films, chemical state and speciation studies. Earlier literature has not been ignored in that some of Archimedes oldest writing, previously hidden from sight in a medieval prayer book has now been revealed thanks to the power of modern m-SRXRF. X-ray optics now benefit from the use of poly-capillaries systems, equipment portability has been extended to include the TXRF configuration and readers will find several papers on the use of both two and three dimensional imaging to support environmental, geological and biological studies. The writing team would welcome feedback from readers of this review and invite you to complete the Atomic Spectrometry Updates questionnaire on www.asureviews.org. 9 Applications 9.1 Sample preparation 9.2 Geological and industrial minerals 9.3 Environmental 9.3.1 Aerosols and particulates 9.3.2 Consequences of industrial activity 9.3.3 Other environmental studies 9.4 Archaeological, cultural heritage and forensic 9.5 Industrial 9.6 Clinical and biological 9.7 Thin films and coatings 9.8 Chemical state and speciation 10 Abbrevations 11 References

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Section: Thin Films and Coatingsmentioning

confidence: 99%

Atomic spectrometry update. X-ray fluorescence spectrometry

West

Ellis²,

Kregsamer

et al. 2008

J. Anal. At. Spectrom.

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“…In this work, films were prepared on a teflon surface. The coating liquid was prepared as reported previously [3]. Eudragit ® L 30 D-55 dispersion was used as polymer, and Diclofenac sodium as API.…”

mentioning

confidence: 99%

Tracking of Physicochemical Properties in Free Films Containing an API

Bölcskei

Regdon²,

Süvegh³

et al. 2010

Sci. Pharm.

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Coated dosage forms in which the active pharmaceutical ingredient (API) is incorporated in the film layer in order to achieve rapid release have become very common in recent years. Our present aim was to develop a matrix pellet containing an API in the coated layer. The presence of insoluble particles in the coating liquid is a critical parameter in the preparation of films as such particles can modify the properties of the film formed [1, 2]. The film surface is required to be smooth, resistant against mechanical effects, heat and light. The excipients and APIs incorporated in a film layer influence the structure of the film significantly. In this work, films were prepared on a teflon surface. The coating liquid was prepared as reported previously [3]. Eudragit ® L 30 D-55 dispersion was used as polymer, and Diclofenac sodium as API. The samples contained 0, 1 and 5% of the API. Measurements were made on the mechanical properties, surface properties and glass transitions of the free films, and on the free volume holes in the films. The mechanical strength and the degree of deformation of the films were determined by the recording of deformation curves. Contact angles were measured to evaluate the surface free energy, solid surface free energy, liquid surface tension and polarity. Glass transition temperatures were detected by means of DSC. Positron annihilation spectroscopy was applied to study the free volume and track interactions between the polymer and the active ingredient. The size distributions of free volume holes were calculated from positron lifetime data for films of different compositions. The long-term stability of films was also studied. Bajdik J, Bölcskei É, Kelemen A, Pintye-Hódi K. Rapid method to study the sedimentation of a pigment suspension prepared for coating fluids.

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“…The pigment suspension was prepared with an UltraTurrax mixer according to our previous results (quantity: 100 g; stirring speed: 17,500 rpm; time: 10 min) [61]. The fluid was mixed in identical cylindrical glass beakers (7.70 cm in diameter) with a magnetic stirrer (IKA-Werke GmbH & Co. Kg, Staufen, Germany).…”

Section: Factorial Designmentioning

confidence: 99%

Optimization of process parameters of coated pellet production

Bölcskei¹

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Rapid method to study the sedimentation of a pigment suspension prepared for coating fluids

Cited by 3 publications

References 13 publications

Atomic spectrometry update. X-ray fluorescence spectrometry

Atomic spectrometry update. X-ray fluorescence spectrometry

Tracking of Physicochemical Properties in Free Films Containing an API

Optimization of process parameters of coated pellet production

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