Rapid induction of granule cell elimination in the olfactory bulb by noxious stimulation in mice

Komano-Inoue, Sayaka; Murata, Katsumi; Mori, Kensaku; Yamaguchi, Masahiro

doi:10.1016/j.neulet.2015.05.002

Cited by 6 publications

(3 citation statements)

References 21 publications

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“…These findings raised the further question of whether enhanced GC elimination occurs only during the postprandial behaviors or during other behavioral states also. Komano-Inoue et al [ 40 ] examined whether fear responses to noxious stimuli induce GC elimination. Mice delivered an electrical foot shock showed startle and fear responses during and immediately after shock delivery.…”

Section: Understanding the New Neurons In The Olfactory Bulb Within Tmentioning

confidence: 99%

Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain

et al. 2015

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Neurons and glia in the central nervous system (CNS) originate from neural stem cells (NSCs). Knowledge of the mechanisms of neuro/gliogenesis from NSCs is fundamental to our understanding of how complex brain architecture and function develop. NSCs are present not only in the developing brain but also in the mature brain in adults. Adult neurogenesis likely provides remarkable plasticity to the mature brain. In addition, recent progress in basic research in mental disorders suggests an etiological link with impaired neuro/gliogenesis in particular brain regions. Here, we review the recent progress and discuss future directions in stem cell and neuro/gliogenesis biology by introducing several topics presented at a joint meeting of the Japanese Association of Anatomists and the Physiological Society of Japan in 2015. Collectively, these topics indicated that neuro/gliogenesis from NSCs is a common event occurring in many brain regions at various ages in animals. Given that significant structural and functional changes in cells and neural networks are accompanied by neuro/gliogenesis from NSCs and the integration of newly generated cells into the network, stem cell and neuro/gliogenesis biology provides a good platform from which to develop an integrated understanding of the structural and functional plasticity that underlies the development of the CNS, its remodeling in adulthood, and the recovery from diseases that affect it.

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Section: Understanding the New Neurons In The Olfactory Bulb Within Tmentioning

confidence: 99%

Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain

et al. 2015

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“…However, the consequences of stress events on the OB plasticity are not yet clear, probably due to species and susceptibility's window differences. Whereas a stressful event rapidly induces granule cell death in adults (Komano-Inoue et al, 2015), a prenatal stress has no impact on adult bulbar neurogenesis and plasticity in mice (Belnoue et al, 2013).…”

Section: Stressmentioning

confidence: 97%

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Duchamp‐Viret

Kuszewski

Baly

2023

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“…For example, elimination of new GCs is enhanced during the sleep period after eating, and is dependent on the centrifugal inputs from the OC during post-meal sleep (Yokoyama et al, 2011; Yamaguchi et al, 2013; Komano-Inoue et al, 2014). GC elimination is also enhanced by the delivery of an electrical foot shock, depending on the centrifugal inputs from the OC during startle and fearful responses (Komano-Inoue et al, 2015). …”

Section: Olfactory Bulb Integrates Peripheral Odor Inputs and Centralmentioning

confidence: 99%

Functional Sub-Circuits of the Olfactory System Viewed from the Olfactory Bulb and the Olfactory Tubercle

Yamaguchi

2017

Front. Neuroanat.

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Understanding of the olfactory neural circuits has progressed beyond analysis of how odor information from the external environment is processed in the brain. While spatially-organized sub-circuits were found to exist up to the olfactory bulb (OB), the arrangement in the olfactory cortex (OC), especially in its representative piriform cortex (PC), appears diffuse and dispersed. An emerging view is that the activity of OC neurons may not simply encode odor identity but rather encode plastic odor information such as odor value. Although many studies support this notion, odor value can be either positive or negative, and the existence of sub-circuits corresponding to individual value types is not well explored. To address this question, I introduce here two olfactory areas other than the PC, OB and olfactory tubercle (OT) whose analysis may facilitate understanding of functional sub-circuits related to different odor values. Peripheral and centrifugal inputs to the OB are considered to relate to odor identity and odor value, respectively and centrifugal inputs to the OB potentially represent different odor values during different behavioral periods. The OT has spatially-segregated functional domains related to distinct motivated and hedonic behaviors. Thus, the OT provides a good starting point from which functional sub-circuits across various olfactory regions can be traced. Further analysis across wide areas of the olfactory system will likely reveal the functional sub-circuits that link odor identity with distinct odor values and direct distinct odor-induced motivated and hedonic behaviors.

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Rapid induction of granule cell elimination in the olfactory bulb by noxious stimulation in mice

Cited by 6 publications

References 21 publications

Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain

Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain

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Functional Sub-Circuits of the Olfactory System Viewed from the Olfactory Bulb and the Olfactory Tubercle

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