Rapid Growth of Basal Cell Carcinoma in a Multigestational Pregnancy

Rapid Progression of a Basal Cell Carcinoma After Photodynamic Therapy

“…The occurrence of the papule may have been coincidental, but the temporal relationship and brisk development of the papule raises the possibility that PDT may have been a precipitating factor. Rapid growth of a BCC in a woman pregnant with twins has been reported and attributed to circulating growth factors related to pregnancy 13 . Rapid development of keratoacanthomas has been reported after laser resurfacing 14 and attributed possibly to trauma or inflammation, but accelerated growth of a BCC after PDT is a phenomenon not previously reported.…”

Basal Cell Carcinoma in Young Patients

“…[1][2][3] During pregnancy, cancers are unusual and BCC has a very low incidence. 5 Cervical cancer, breast cancer, malignant melanoma, and lymphoma are the most commonly reported cancers during pregnancy. 5 Fisher et al 5 reported a 42-year-old woman who had a rapid growth of BCC during multi-gestational pregnancy, but it did not have a rapid growth during mono-gestational pregnancy.…”

“…The most common type of skin cancer and the most common type of cancer found in people is basal cell carcinoma (BCC), which peaks in the seventh decade. [1][2][3][4][5][6][7][8][9][10][11] It was first described in 1827 and was called "ulcus rodens". 3,4 It originates from the basal layer of the epidermis or hair follicle keratinocytes.…”

“…3 It is uncommon during childhood, youth, and pregnancy. [1][2][3][4][5]9 Sporadic BCC in children and cancer occurring during the gestational period have rarely been reported. 1,2,4,7 Surgical excision is the usual treatment during childhood.…”