Rapid detection of <i>Candida albicans</i> in urine by an Electrochemical Impedance Spectroscopy (EIS)-based biosensor

D'Aponte, Tina; De Luca, Maria; Sakač, Nikola; Schibeci, Martina; Arciello, Angela; Roscetto, Emanuela; Catania, Maria Rosaria; Iannotti, Vincenzo; Velotta, Raffaele; Della Ventura, Bartolomeo

doi:10.1039/d3sd00209h

Cited by 1 publication

(1 citation statement)

References 41 publications

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“…Moreover, the fluidics ensured the uniform distribution of samples and reagents across the sensing area, guaranteeing consistent and reliable measurements while minimizing variations due to manual handling. [35] A volume of 1 mL of Abs solution in PBS activated by PIT, flowed onto the plasmonic surface. The concentration of Abs was fixed to 2.5 μg mL −1 , ensuring a red-shift of approximately 6.5 nm (Figure 3b).…”

Section: Functionalization and Analyte's Recognition Of Aunps Surfacementioning

confidence: 99%

Beyond the Passive Diffusion: Core@Satellite Magneto‐Plasmonic Particles for Rapid and Sensitive Colorimetric Immunosensor Response

De Luca,

Acunzo,

Marra

et al. 2024

Advanced Sensor Research

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Magneto‐plasmonic particles, comprising gold and iron oxide, exhibit substantial potential for biosensing applications due to their distinct properties. Gold nanoparticles (AuNPs) provide plasmonic features, while iron oxide composites, responsive to an external magnetic field, significantly reduce detection time compared to passive diffusion. This study explores core@satellite magneto‐plasmonic particles (CSMPs), featuring magnetic nanoparticle clusters and numerous satellite‐like AuNPs, to amplify the optical response on a nanostructured gold surface. Using a sandwich scheme, target analytes are detected as hybrid nanoparticles bind to the pre‐immobilized target on the AuNPs surface, inducing changes in the immunosensor's extinction spectrum. Application of an external magnetic field notably enhances biosensor response and sensitivity, reducing assay time from hours to minutes. Leveraging the properties of CSMPs, the immunosensor detects specific immune protein at low concentrations within minutes. CSMPs hold considerable promise for precise and sensitive analyte detection, offering potential applications in rapid testing and mass screening.

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Section: Functionalization and Analyte's Recognition Of Aunps Surfacementioning

confidence: 99%

Beyond the Passive Diffusion: Core@Satellite Magneto‐Plasmonic Particles for Rapid and Sensitive Colorimetric Immunosensor Response

De Luca,

Acunzo,

Marra

et al. 2024

Advanced Sensor Research

Self Cite

View full text Add to dashboard Cite

show abstract

Rapid detection of Candida albicans in urine by an Electrochemical Impedance Spectroscopy (EIS)-based biosensor

Abstract: Candida albicans is a fungal organism commonly found in the human body, including the genitourinary tract.

Cited by 1 publication

References 41 publications

Beyond the Passive Diffusion: Core@Satellite Magneto‐Plasmonic Particles for Rapid and Sensitive Colorimetric Immunosensor Response

Beyond the Passive Diffusion: Core@Satellite Magneto‐Plasmonic Particles for Rapid and Sensitive Colorimetric Immunosensor Response

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