Rapid confirmatory analysis of avermectin residues in milk by liquid chromatography tandem mass spectrometry

Özdemir, Nurullah; Kahraman, Tahir

doi:10.1016/j.jfda.2015.07.004

Cited by 18 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, chemical fingerprint analysis has been applied as an effective method for milk and dairy products quality control. These fingerprinting methods include HPLC [ 5 ], capillary electrophoresis [ 8 ], isoelectric focusing [ 9 , 10 ], enzyme-linked immunosorbent assay [ 11 ], PCR technology [ 6 , 12 ], pulse polarography method [ 13 ], liquid chromatography tandem mass spectrometry [ 14 ] and so on. Most of these methods exhibit high sensitivity and can meet the requirements for identifying and evaluating adulteration of milk and dairy products.…”

Section: Introductionmentioning

confidence: 99%

Identification of cow milk in goat milk by nonlinear chemical fingerprint technique

Wang

Fan

et al. 2017

Journal of Food and Drug Analysis

View full text Add to dashboard Cite

The objective of this paper was to develop a nonlinear chemical fingerprint technique for identifying and detecting adulteration of goat milk with cow milk. In this study, by taking the Belousov-Zhabotinsky oscillatory chemical reaction using acetone and substrates in goat milk or cow milk as main dissipative substances, when the same dosage of goat milk and cow milk was introduced to the "H + Mn + BrO + acetone" oscillating system respectively, nonlinear chemical fingerprints were obtained for goat milk and cow milk from the same origin. The results showed that inductive time value and the content of cow milk in goat milk had a linear relationship in the range of 0-100% and the corresponding regression coefficient was 0.9991. A detection limit of 0.0107 g/g was obtained, and the content of cow milk in mixed milk was calculated. The proposed method in this study was simple, economical and effective. In addition, the method did not need the pretreatment and separation of samples for identifying and evaluating cow milk adulteration in goat milk.

show abstract

Section: Introductionmentioning

confidence: 99%

Identification of cow milk in goat milk by nonlinear chemical fingerprint technique

Wang

Fan

et al. 2017

Journal of Food and Drug Analysis

View full text Add to dashboard Cite

show abstract

“…Sulfathiazole and tilmicosin compounds were providing recovery rates up to 200% and high standard deviations up to 60% measured in mostly low spiked sample matrices. Ozdemir and Kahraman [ 43 ] developed a method for quick and confirmatory analysis of avermectins (doramectin, abamectin B1a, eprinomectinB1a, moxidectin, and ivermectin B1a) in bovine milk as per regulations 2002/657/EC requirements. The validation parameters were specificity, linearity, recovery, LOD, LOQ, DL, and DC.…”

Section: Lc-msmentioning

confidence: 99%

Assessment of various veterinary drug residues in animal originated food products

Parmar

Chaubey

Gupta³

et al. 2021

Vet World

View full text Add to dashboard Cite

The veterinary drugs are broad-spectrum antibacterial antibiotics; it uses to cure the animal disease. Many countries have banned veterinary drug residues like nitrofurans metabolites, chloramphenicol. However, the people were administrated veterinary drugs to animals as illegal to increase the milk production in animals for economic benefit. The results of illegally use of veterinary drugs remain as a residue in animal product like milk and it is very harmful to whom consume it cause cancer and allergic for human being which has entered the concern among milk consumers. To control illegal use of veterinary drugs, the government of India has restricted its use in animals. For the identification and confirmation of veterinary drug residues in animal products, analytical techniques such as liquid chromatography and mass spectrometry are available. These are very sophisticated equipments which are available nowadays and their methodologies for the analytical method validation are described by European commission 2002/657/EC. The use of veterinary drugs is a big challenge to effectively identify and authorization of their use. There are so many analytical techniques are using very effectively and taking very less time to protect the consumers from their adverse effects. These techniques take very less time to identify more groups of compounds such as tetracycline, sulfonamides, anthelmintic, and macrolides in single multi-residue method. These methods having validation parameters include system precision, calibration curve, accuracy, limit of detection, and quantification. Therefore, improvement in the existing technologies and accessibility of new screening methodologies will give opportunities for automation that helps in obtaining the results in very less time and improved sensitivity and specificity which contribute to better safety assurance, standard, and quality of various food products of animal origin.

show abstract

“…It has higher sensitivity and encompasses wide range of analytes. The residual content of all avermectins in animal products can be determined with the help of UHPLC-MS/MS (Nurullah Ozdemir and Tahir Kahraman, 2016;Durden, 2006). Some methods developed for ultra high-performance liquid chromatography-mass spectrometers are highly costly, especially those that are designed to use solid-phase columns for better cleaning of the supernatant.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Ultra-High-Performance Liquid Chromatography (HPLC) Tandem Mass Spectrometry for Determination of Avermectin Residues in Milk

Bayer¹,

Kaminska²,

Bondarets³

et al. 2019

Ukr J Ecol

View full text Add to dashboard Cite

The study was conducted to evaluate the applicability of ultra high-performance liquid chromatography - tandem mass spectrometry method (UHPLC-MS/MS), establish the MS/MS detection parameters and determine the validation characteristics for the analysis of residual content of avermectins in milk. The UHPLC-MS/MS method has proved to be accurate, practical and universal. This was confirmed by Decision limit (CCα) data: abamectin - 12.56 μg/kg, doramectin - 17.74 μg/kg, eprinomectin - 24.02 μg/kg, ivermectin - 12.53 μg/kg, moxidectin - 44.69 μg/kg, recovery is 88.7-110%. The data obtained for assessing the suitability, accuracy and reproducibility of the results meet the requirements of the European Directive (2002/657/EC). The efficient ultra high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method that was developed and adopted for routine use by the laboratories of veterinary medicine, allows to detect residual quantities of 5 avermectins used in animal breeding for the prevention of helminthiases in food products including milk.

show abstract

Rapid confirmatory analysis of avermectin residues in milk by liquid chromatography tandem mass spectrometry

Cited by 18 publications

References 4 publications

Identification of cow milk in goat milk by nonlinear chemical fingerprint technique

Identification of cow milk in goat milk by nonlinear chemical fingerprint technique

Assessment of various veterinary drug residues in animal originated food products

Evaluation of Ultra-High-Performance Liquid Chromatography (HPLC) Tandem Mass Spectrometry for Determination of Avermectin Residues in Milk

Contact Info

Product

Resources

About