Rapid Changes in Autonomic Reflexes Induced by Pentothal

Effect of propofol on heart rate, arterial pressure and digital plethysmograph variability

“…Inhalation [9][10][11] and i.v. [12][13][14][15] anaesthetics, nitrous oxide [16], opioids [17], benzodiazepines [18], artificial ventilation [19] and surgical stimulation [20] have significant effects on HRV [21][22][23][24]. In general, with the onset of anaesthesia a marked reduction in variability in all frequency bands is observed, although the relative proportion of power in these bands may vary according to the effect of the anaesthetic on autonomic, respiratory and cardiovascular function.…”