“…In the context of routine immunohematology, serological techniques enable us to characterize most of the Rh phenotypes, and within the last decade, molecular biology solutions have helped compensate for the main limitations of serological techniques [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. Still, in some situations, ambiguities or discrepancies cannot be resolved, especially for RhCE, and uncertainties remain regarding the transfusion instructions; in this context, the French Blood Center, whose main mission is to ensure France’s self-sufficiency in blood products under optimal safety and quality conditions, is continuously setting up molecular typing strategies in line with technological developments [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ].…”