Rapid and specific detection of LDL based on light addressable potentiometric sensor decorated with reduced graphene oxide-polyaniline-hemin nanocomposites

Li, Guiyin; Li, Shengnan; Huang, Qing; Li, Xinhao; Zhang, Zhengyu; Liang, Jintao; Zhou, Zhide

doi:10.1016/j.microc.2023.109314

Cited by 3 publications

(1 citation statement)

References 40 publications

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“…As for the applications, many studies are directed to biosensing applications, including the detection of DNA hybridization [56,91], determination of glucose [92,93] and okadaic acid [94], as well as immunoassays of antigens [95]. Many studies are especially oriented to the detection of clinical biomarkers such as circulating tumor cells [96], alphafetoprotein [97], 1,5-anhydroglucitol [98], glypican-3 [99], and low-density lipoprotein [100]. The light-addressing technologies are also applied to cells, including the detection of extracellular acidification due to metabolism [67,101], light absorption of live cells [102], action potentials of cardiomyocytes [103], and apoptosis [104].…”

Section: Discussionmentioning

confidence: 99%

Field-Effect Sensors Combined with the Scanned Light Pulse Technique: From Artificial Olfactory Images to Chemical Imaging Technologies

Yoshinobu,

Miyamoto,

Wagner

et al. 2024

Chemosensors

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The artificial olfactory image was proposed by Lundström et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices.

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Section: Discussionmentioning

confidence: 99%

Field-Effect Sensors Combined with the Scanned Light Pulse Technique: From Artificial Olfactory Images to Chemical Imaging Technologies

Yoshinobu,

Miyamoto,

Wagner

et al. 2024

Chemosensors

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Carbon-based light addressable potential sensor based on nitrogen-doped graphene quantum dots for detection of low-density lipoprotein

Li,

Wu,

Yan

et al. 2024

Microchemical Journal

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Utilization of a TiO2–CuO Bimetallic/Polyaniline Nanocomposite as a Transducer in a Solid Contact Potentiometric Sensor for the Determination of Vildagliptin

Abdallah,

Ahmed,

Almaghrabi

et al. 2023

Polymers

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Current fundamental electrochemical research shows the potential of utilizing polymeric nanostructured materials as ion-to-electron transducers. In this paper, aniline was polymerized in the presence of TiO2 and CuO nanoparticles to yield a bimetallic/PANI nanocomposite. It was applied as a transducer in a carbon paste electrode for the potentiometric determination of vildagliptin in the presence of 18-crown-6-ether as a recognition element. The electrode’s potentiometric performance was studied according to the IUPAC guidelines. It exhibited a wide linearity range of 1 × 10−2 M to 1 × 10−8 M, remarkable sensitivity (LOD of 4.5 × 10−9 M), and a fast response time of 10 s ± 1.3. The sensor did not show any potential drift due to the absence of the water layer between the carbon paste and the metallic conductor. This endowed the sensor with high stability and a long lifetime, as 137 days passed without the need to change the carbon paste surface. The electrode was utilized for the determination of the concentration of vildagliptin in bulk, pharmaceutical tablets, and human plasma, with average recovery ranging from 97.65% to 100.03%.

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Rapid and specific detection of LDL based on light addressable potentiometric sensor decorated with reduced graphene oxide-polyaniline-hemin nanocomposites

Cited by 3 publications

References 40 publications

Field-Effect Sensors Combined with the Scanned Light Pulse Technique: From Artificial Olfactory Images to Chemical Imaging Technologies

Field-Effect Sensors Combined with the Scanned Light Pulse Technique: From Artificial Olfactory Images to Chemical Imaging Technologies

Carbon-based light addressable potential sensor based on nitrogen-doped graphene quantum dots for detection of low-density lipoprotein

Utilization of a TiO2–CuO Bimetallic/Polyaniline Nanocomposite as a Transducer in a Solid Contact Potentiometric Sensor for the Determination of Vildagliptin

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