“…There are some methods for analysis of BB in biological samples, such as capillary electrophoresis [ 32 , 33 ], a flow-injection chemiluminescence system [ 34 ], near-infrared spectroscopy [ 35 ], the UPLC–MS/MS method [ 36 , 37 ], and HPLC with MS/MS [ 38 – 43 ] or a UV detector [ 44 , 45 ]. These methods focus on the fecal sample [ 32 ], plasma [ 33 , 36 – 43 ], and herbal or herbal preparations [ 34 , 35 , 44 , 45 ]. A few methods pay close attention to the determination of BB in tissues [ 46 – 48 ], in which some needed a two-step extraction [ 46 , 47 ] and one used the HPLC/MS/MS system [ 48 ].…”