Rapid and Sensitive Determination of Vanillin Based on a Glassy Carbon Electrode Modified with Cu2O-Electrochemically Reduced Graphene Oxide Nanocomposite Film

Ning, Jingheng; He, Quanguo; Luo, Xin; Wang, Min; Liu, Donglin; Wang, Jianhui; Liu, Jun; Li, Guangli

doi:10.3390/s18092762

Cited by 41 publications

(19 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to a previous report [38], Cu 2 O nanoparticles (Cu 2 O NPs) were synthesized by the wet-chemical method. Following a typical process, 100 mg of CuSO 4 ·5H 2 O and 50 mg of PVP were added into 20 mL of H 2 O with stirring.…”

Section: Synthesis Of Cu 2 O Nanoparticlesmentioning

confidence: 99%

“…The different morphologies of Cu 2 O nanomaterials, such as hollow spheres, cubes, wires, octahedrons and cages, can be synthesized by adjusting the synthesis conditions [28]. At present, various electrochemical sensors based on Cu 2 O nanoparticles have been constructed for the detection of H 2 O 2 [29,30], glucose [30][31][32], dopamine [33][34][35], herbicide paraquat [36], L-tyrosine [37], vanillin [38], sunset yellow [39] and NO 2 [40]. As far as we know, the use of Cu 2 O for the determination of UA has rarely been reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Determination of Uric Acid in Co-Presence of Dopamine and Ascorbic Acid Using Cuprous Oxide Nanoparticle-Functionalized Graphene Decorated Glassy Carbon Electrode

Ning

Luo

et al. 2018

Catalysts

Self Cite

View full text Add to dashboard Cite

Cuprous oxide nanoparticles (Cu 2 O NPs) were dispersed into a graphene oxide (GO) solution to form a homogeneous Cu 2 O-GO dispersion. After this, the cuprous oxide nanoparticles were functionalized to electrochemically reduce the graphene oxide decorated glassy carbon electrode (Cu 2 O-ErGO/GCE). This was prepared by coating the Cu 2 O-GO dispersion onto the surface of the glassy carbon electrode (GCE), which was followed by a potentiostatic reduction process. An irreversible two-electron reaction of uric acid (UA) was observed at the voltammetric sensor. Moreover, the high concentrations of dopamine (DA) and ascorbic acid (AA) hardly affected the peak current of UA, which suggested that Cu 2 O-ErGO/GCE have excellent selectivity for UA. This is probably because the response peaks of the three compounds are well-separated from each other. The oxidation peak current was proportional to the concentration of UA in the ranges of 2.0 nM−0.6 µM and 0.6 µM−10 µM, respectively, with a low limit of detection (S/N = 3, 1.0 nM) after an accumulation time of 120 s. Cu 2 O-ErGO/GCE was utilized for the rapid detection of UA in human blood serum and urine samples with satisfactory results. when detecting UA with bare electrodes since they have similar oxidation peak potentials [10][11][12]. Nanocomposite-modified electrodes can improve the anti-interference performance and selectivity, which is a common method that is used to solve this problem. At present, many chemically modified electrodes have been proposed for the determination of UA [9,[13][14][15][16][17][18][19][20][21][22] although their selectivity is limited, especially due to the coexistence of DA and AA. Hence, developing a modified electrode with high sensitivity and selectivity to meet clinical demands is still challengeable and desirable.Catalysts 2018, 8, x FOR PEER REVIEW 2 of 15 potentials [10][11][12]. Nanocomposite-modified electrodes can improve the anti-interference performance and selectivity, which is a common method that is used to solve this problem. At present, many chemically modified electrodes have been proposed for the determination of UA [9,[13][14][15][16][17][18][19][20][21][22] although their selectivity is limited, especially due to the coexistence of DA and AA. Hence, developing a modified electrode with high sensitivity and selectivity to meet clinical demands is still challengeable and desirable. Scheme 1. The reaction mechanism of UA.In the past few years, transition metals and metal oxides have received increasing attention in many fields, such as sensors and electrocatalysis, due to their unique sensing performance and superior electrocatalytic activity [9,11,23,24]. Among these metal oxides, cuprous oxide (Cu2O) is a new type of p-type semiconductor with a narrow band gap, which can also be easily excited by visible light. Due to their outstanding advantages, such as non-toxic, low cost and stable photochemical properties, Cu2O nanoparticles have been extensively used in many fields, such as new energy, photocatalytic degradation, ...

show abstract

Section: Synthesis Of Cu 2 O Nanoparticlesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Determination of Uric Acid in Co-Presence of Dopamine and Ascorbic Acid Using Cuprous Oxide Nanoparticle-Functionalized Graphene Decorated Glassy Carbon Electrode

Ning

Luo

et al. 2018

Catalysts

Self Cite

View full text Add to dashboard Cite

show abstract

“…There are a lot of methods for Cu 2 + detection, mainly including high performance liquid chromatography (HPLC) [8], atomic absorption spectrometry (AAS) [9], atomic fluorescence spectrometry (AFS) [10] and inductively coupled plasma mass spectrometry (ICP-MS) [11]. However, these conventional methods have obvious limitations such as relatively expensive instruments and complicated timeconsuming operations, so not convenient to be applied for on-site or special-site detection [12][13]. Therefore, it has become very necessary to develop highly effective or economical methods for copper detection.…”

Section: Introductionmentioning

confidence: 99%

Highly Hydrophilic Polymer Composite Modified Electrode for Trace Copper Detection Based on Synergetic Electrostatic Attractions and Chelating Interactions

Wang

Liu

et al. 2020

Electroanalysis

Self Cite

View full text Add to dashboard Cite

A new electrochemical sensor for Cu 2 + detection by square wave voltammetry with high sensitivity has been constructed, based on a composite of sodium carboxymethyl cellulose and Nafion. Starting from these two polymers that are rich of hydrophilic groups in backbones, a highly negative-charged composite has been easily prepared, which displays outstanding ability to adsorb and enrich Cu 2 + onto the electrode surface through both electrostatic attractions and chelating interactions. After optimizing test conditions, this new sensor exhibits a good linear signal response to Cu 2 + in a concentration range from 1.0 nΜ to 50.0 nM with a limit of detection of 0.6 nM (S/N = 3), as well as good antiinterference for commonly co-existing metal ions. Besides, this new electrochemical copper sensor has been successfully applied to detect trace Cu 2 + in natural water samples with satisfactory recoveries of 98-104 %. These findings provide a new simple but effective way for the determination of heavy metal ions in environmental pollutants.

show abstract

“…Comparatively, the electrochemical analysis method seems to be more attractive and practicable due to its remarkable sensitivity, simplicity, and low cost [18]. Among the electrochemical methods, differential pulse anodic stripping voltammetry (DPASV) has been successfully used to detect heavy metal ions, which is usually based on special chemically-modified electrodes [19,20]. For a long time, mercury-modified electrodes, mainly including hanging drop mercury and thin mercury film electrodes, were the typical chemically modified electrodes, as they showed good results in stripping analysis of heavy metals [21,22].…”

Section: Introductionmentioning

confidence: 99%

Synergetic Sensing Effect of Sodium Carboxymethyl Cellulose and Bismuth on Cadmium Detection by Differential Pulse Anodic Stripping Voltammetry

Ning

Luo

Wang

et al. 2019

Sensors

Self Cite

View full text Add to dashboard Cite

In the present work, a novel electrochemical sensor was developed for the detection of trace cadmium with high sensitivity and selectivity in an easy and eco-friendly way. Firstly, a glassy carbon electrode (GCE) was modified with nontoxic sodium carboxymethyl cellulose (CMC) by a simple drop-casting method, which was applied to detect cadmium by differential pulse anodic stripping voltammetry (DPASV) in a solution containing both target cadmium and eco-friendly bismuth ions, based on a quick electro-codeposition of these two metal ions on the surface of the modified electrode (CMC-GCE). Investigated by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and Fourier transform infrared spectroscopy (FT-IR), both CMC (with good film-forming ability) and bismuth (with well-defined stripping signal) were found to be well complexed with target cadmium, leading to vital signal amplification for cadmium detection at a sub-nanomolar level. Under the optimal conditions, the proposed sensor exhibited a good linear stripping signal response to cadmium (Ⅱ) ion, in a concentration range of 0.001 μmol/L–1 μmol/L with a limit of detection of 0.75 nmol/L (S/N = 3). Meanwhile, the results demonstrate that this novel electrochemical sensor has excellent sensitivity and reproducibility, which can be used as a promising detection technique for testing natural samples such as tap water.

show abstract

Rapid and Sensitive Determination of Vanillin Based on a Glassy Carbon Electrode Modified with Cu2O-Electrochemically Reduced Graphene Oxide Nanocomposite Film

Cited by 41 publications

References 35 publications

Determination of Uric Acid in Co-Presence of Dopamine and Ascorbic Acid Using Cuprous Oxide Nanoparticle-Functionalized Graphene Decorated Glassy Carbon Electrode

Determination of Uric Acid in Co-Presence of Dopamine and Ascorbic Acid Using Cuprous Oxide Nanoparticle-Functionalized Graphene Decorated Glassy Carbon Electrode

Highly Hydrophilic Polymer Composite Modified Electrode for Trace Copper Detection Based on Synergetic Electrostatic Attractions and Chelating Interactions

Synergetic Sensing Effect of Sodium Carboxymethyl Cellulose and Bismuth on Cadmium Detection by Differential Pulse Anodic Stripping Voltammetry

Contact Info

Product

Resources

About