“…Such described methods include traditional techniques like high performance liquid chromatography with UV detection [21][22][23][27][28][29][30]32,34,36,41] and high performance liquid chromatography with fluorescence (FL) detection [24,26,31,33,37,40,42] as well as new techniques as high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) [25,38,39], ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) [35]. Not all of these assays are appropriate for rapid pharmaceutical analysis of LVF in clinical and research practice.…”