Rapid and scalable scans at 21  m/s in optical low-coherence reflectometry

Ballif, Julien J.; Gianotti, R.; Chavanne, Ph.; Wälti, R.; Salathé, R. P.

doi:10.1364/ol.22.000757

Cited by 58 publications

(19 citation statements)

References 15 publications

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“…The OLCR pachymeter was attached to a BC 900 slit-lamp (both from Haag-Streit,) (Ballif et al 1997;Genth et al 2002). The OLCR pachymeter was calibrated and used as described in the instruction manual.…”

Section: Equipmentmentioning

confidence: 99%

Central corneal thickness in high myopia

Pedersen

Hjortdal

Ehlers

2005

Acta Ophthalmologica Scandinavica

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ABSTRACT.Purpose: To examine if central corneal thickness (CCT) is different in emmetropia and high myopia. Methods: 57 emmetropic subjects (0 to + 1.5 D) and 48 high myopes (all more than -6 D in spherical equivalent refraction) were studied. CCT was measured by a Haag-Streit Optical Low-Coherence Reflectometry (OLCR) pachymeter, a recently developed high precision pachymeter with a standard deviation (SD) for repeated measurements of 1 mm. Results: Mean CCT for the emmetropic group was 538.6 mm (SD = 32.1), and for the myopic group 527.7 mm (SD = 35.0). Neither the mean CCT nor the variance from the two groups showed a statistically significant different (p > 0.05). Conclusion: CCT is not systematically altered in myopia. The process by which the myopia progresses does not to a measurable degree influence the central cornea.

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Section: Equipmentmentioning

confidence: 99%

Central corneal thickness in high myopia

Pedersen

Hjortdal

Ehlers

2005

Acta Ophthalmologica Scandinavica

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“…The design of the optical reflectometer is based on a Michelson interferometer constructed with single-mode optical fibers. Details of the design of the rapid optical pachometer have previously been reported [28]. The OLCR measurements of corneal thickness can be performed with high precision of about one micron and high intra-and intersession reproducibility [29][30][31][32].…”

Section: Overnight Lid Closure and The Reversible Micro-folds In The mentioning

confidence: 99%

Correlation of histology and linear and nonlinear microscopy of the living human cornea

Masters

2009

Journal of Biophotonics

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Journal of BIOPHOTONICSThe morphology and the function of cellular and noncellular structures in the living human cornea can be determined with modern correlative linear and nonlinear optical microscopic techniques and histology. Correlative microscopy is based on the use of different optical techniques to study the same specimen, ideally at the same location within the specimen, in order to increase the functional and/or morphological understanding of the specimen. A case study to assess the effect of overnight lid-closure on in vivo human corneal morphology is presented to illustrate correlative linear microscopy and optical low-coherence reflectometry. Nonlinear multiphoton excitation microscopy provides functional information on cellular metabolism based on the intrinsic fluorescence from the reduced pyridine nucleotides and the oxidized flavoproteins. Second-harmonic generation microscopy, a scattering process that does not deposit net energy into the tissue, provides structural information on corneal collagen organization. Molecular thirdharmonic generation microscopy generates a signal in all materials and it an emerging technique. Coherent antiStokes Raman scattering microscopy provides chemical imaging for biology and medicine. The comparison and limitations of these microscopic modalities, linear and nonlinear microscopy applied to the cornea, and a review of some key findings is analyzed. A correlative integration and correlation of linear and nonlinear microscopies to study corneal function and structure is proposed to validate the clinical interpretation of microscopic images of the cornea.Confocal microscopy image of in vivo human corneal nerves in the anterior stroma *

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“…However, the position and velocity of the mirror in this setup changes sinusoidally, so the optical delay did not change linearly in time. Then, a rotating cube [3,4] (or a prism [5]) was suggested. In such systems the light is first passed through the rotating cube, then reflected from the stationary mirror and, finally, passed back through the same cube.…”

Section: Introductionmentioning

confidence: 99%

Linear rotary optical delay lines

Guerboukha

2016

Photonic Instrumentation Engineering III

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We present a semi-analytical solution for the design of a high-speed rotary optical delay line that use a combination of two rotating curvilinear reflectors. We demonstrate that it is possible to design an infinite variety of the optical delay lines featuring linear dependence of the optical delay on the rotation angle. This is achieved via shape optimization of the rotating reflector surfaces. Moreover, a convenient spatial separation of the incoming and outgoing beams is possible. For the sake of example, we present blades that fit into a circle of 10cm diameter. Finally, a prototype of a rotary delay line is fabricated using CNC machining, and its optical properties are characterized.

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Rapid and scalable scans at 21 m/s in optical low-coherence reflectometry

Cited by 58 publications

References 15 publications

Central corneal thickness in high myopia

Central corneal thickness in high myopia

Correlation of histology and linear and nonlinear microscopy of the living human cornea

Linear rotary optical delay lines

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