Rapid and reliable detection of bacterial endospores in environmental samples by diagnostic electron microscopy combined with X-ray microanalysis

Laue, Michael; Fulda, Gerhard

doi:10.1016/j.mimet.2013.03.026

Cited by 7 publications

(1 citation statement)

References 19 publications

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“…The SEM images permit the morphological identification of a microorganism, and the X-ray microanalysis can give information on the elemental composition of both the organic and inorganic components. For example, elemental composition data such as a high calcium concentration, can be used to differentiate bacterial spores from other suspicious particles with a similar morphology 14 . In investigating a suspect anthrax powder, its morpohological characteristsics, such as having a high spore concentration, a uniform particle size, and the presence of anti-clumping agents might indicate a material that was deliberately prepared 16 .…”

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confidence: 99%

A mobile biosafety microanalysis system for infectious agents

Beniac

Hiebert

Siemens

et al. 2015

Sci Rep

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Biological threats posed by pathogens such as Ebola virus must be quickly diagnosed, while protecting the safety of personnel. Scanning electron microscopy and microanalysis requires minimal specimen preparation and can help to identify hazardous agents or substances. Here we report a compact biosafety system for rapid imaging and elemental analysis of specimens, including powders, viruses and bacteria, which is easily transportable to the site of an incident.

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confidence: 99%