Rapid and efficient synthesis of symmetrical alkyl disulfides under phase transfer conditions

Co(II) Catalyzed Solvent Free Auto-Oxidation of Methylbenzenes to Substituted Benzoic Acids Under Phase Transfer Conditions

“…The dependence of oxidation rate on oxygen flow rate was investigated in the range of 30-200 ml/min (Entry [19][20][21][22]. Based on these results we concluded that increasing the oxygen flow rate increased the oxidation rate.…”

“…Some years ago we studied the ruthenium catalyzed oxidation of 1-phenyl ethanol to acetophenone using didecyldimethylammonium bromide (DDAB)/H 2 O 2 /dichloroethane system and found unusual PTC mechanism which differed from the classical extraction and interfacial mechanism often encountered in PTC oxidations [18]. Recently, we explored the DDAB as universal, robust and highly potent phase transfer catalyst for various organic transformations [19][20][21]. We have now realized that solid liquid extraction of Cobalt (II) chloride by anion exchange with lipophilic ammonium bromide salts in organic solvent generates a very potent auto-oxidation catalyst for methylbenzenes (Eq.…”

Sodium Sulfide

“…27 The reactivity order was found to be: benzyl halide > primary alkyl halide > secondary alkyl halide > tertiary alkyl halide > aryl halide.…”

Flow Synthesis of Symmetrical Di- and Trisulfides Using Phase-Transfer Catalysis

“…A promising procedure to develop disulfide synthesis in flow chemistry was reported by Sonavane et al utilizing didecyldimethylammonium bromide (DDCB) as a transfer catalyst in the reaction between aqueous sodium disulfide and alkyl halides in chloroform to produce symmetrical disulfides under mild reaction conditions [10]. In this work, several other transfer catalysts, such as tetrabutylammonium bromide (TBAB), were screened.…”

“…Sonavane et al claimed that the reaction shown in Scheme 1 [10] is also suitable for the synthesis of other polysulfides. In the approach to synthesize the corresponding trisulfide, two equivalents of elemental sulfur were added to the disodium sulfide solution for the generation of disodium trisulfide.…”