Rapid and background-free detection of avian influenza virus in opaque sample using NIR-to-NIR upconversion nanoparticle-based lateral flow immunoassay platform

Kim, Jae‐Young; Kwon, Jung‐Hoon; Jang, Jin–Young; Lee, Hyojin; Kim, Seung Ki; Hahn, Young Ki; Kim, Sang Kyung; Lee, Kwan H.; Lee, Seok; Pyo, Heesoo; Song, Chang Seon; Lee, Joon Seok

doi:10.1016/j.bios.2018.04.047

Cited by 86 publications

(48 citation statements)

References 32 publications

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“…Among them, LFAs that use ultra-bright fluorescence nanomaterials with longer fluorescence lifetimes can significantly reduce background noise and enhance LFA detection sensitivity using the time-resolved analysis technique ( Hu et al, 2017a , Hu et al, 2017b ). Additionally, a recent study reported a very promising near-infrared (NIR) wavelength emitting lanthanide-doped nanoparticles (UCNP)-based LFA which exhibits no fluorescence absorbance or auto-fluorescence interference with blood, stools, and nitrocellulose membranes, and can detect disease biomarkers with high accuracy and sensitivity ( Kim et al, 2018 ; Liu et al, 2020a , Liu et al, 2020b ). Compared to fluorescence LFA detection, magnetic nanoparticle-based detection produces a much lower background magnetic signal, has a higher signal-noise ratio, and can detect disease biomarkers with higher sensitivity.…”

Section: Potential Biosensors For Point-of-care Sars-cov-2 Detectionmentioning

confidence: 99%

Detection of COVID-19: A review of the current literature and future perspectives

Liu

Wang

et al. 2020

Biosensors and Bioelectronics

325

309

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The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This unprecedented situation has garnered worldwide attention. An effective strategy for controlling the COVID-19 pandemic is to develop highly accurate methods for the rapid identification and isolation of SARS-CoV-2 infected patients. Many companies and institutes are therefore striving to develop effective methods for the rapid detection of SARS-CoV-2 ribonucleic acid (RNA), antibodies, antigens, and the virus. In this review, we summarize the structure of the SARS-CoV-2 virus, its genome and gene expression characteristics, and the current progression of SARS-CoV-2 RNA, antibodies, antigens, and virus detection. Further, we discuss the reasons for the observed false-negative and false-positive RNA and antibody detection results in practical clinical applications. Finally, we provide a review of the biosensors which hold promising potential for point-of-care detection of COVID-19 patients. This review thereby provides general guidelines for both scientists in the biosensing research community and for those in the biosensor industry to develop a highly sensitive and accurate point-of-care COVID-19 detection system, which would be of enormous benefit for controlling the current COVID-19 pandemic.

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Section: Potential Biosensors For Point-of-care Sars-cov-2 Detectionmentioning

confidence: 99%

Detection of COVID-19: A review of the current literature and future perspectives

Liu

Wang

et al. 2020

Biosensors and Bioelectronics

325

309

View full text Add to dashboard Cite

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“…One of the most promising assays platforms, the lateral flow assay (LFA) platform has advantages, providing point-ofcare and on-site monitoring extensively established for the detection of various analytes. As shown in Figure 4A, an avian influenza virus (AIV) assay has a LOD 10-times lower than that of the commercial gold nanoparticle-based AIV LFA kit, even with opaque samples 32 . The LOD of the AIV LFA kit for low pathogenicity avian influenza (LPAI) H5N2 and high pathogenicity avian influenza (HPAI) H5N6 viruses was 10 2 and 10 3.5 EID 50 /mL, respectively 32 .…”

Section: Heterogenous Assaymentioning

confidence: 99%

Lanthanide-Doped Upconversion Nanomaterials: Recent Advances and Applications

et al. 2020

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Lanthanide-doped upconversion nanomaterials are well known for converting near-infrared (NIR) excitation photons into visible, ultraviolet, and NIR emission photons. Excitation of NIR light offers low autofluorescence background and high penetration depth in biological environments due to the reduced light scattering. Consequently, these have attracted considerable interest because their exceptional optical properties have led to applications in diverse areas such as bioassays, biomedical imaging, and forensics; these properties are, namely: large anti-Stokes shifts, sharp emission spectra and long excited-state lifetimes. The nanomaterials can be utilized for a variety of applications including detection of various analytes, bioimaging, therapies, energy conversion, and security. In this review, we briefly describe the upconversion luminescence process, effective synthetic approaches, and recent literature that elucidate the exceptional properties of these materials and its applications.

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“…So far, we have reviewed at methods of detection using the HA protein of IV. However, there is also a method of detecting IV using an internal protein with few mutations 82,83 .…”

Section: Optical-based Aptasensor For IV Detectionmentioning

confidence: 99%

Recent Development of Aptasensor for Influenza Virus Detection

Kim

Noh

et al. 2020

BioChip J

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In nowadays, we have entered the new era of pandemics and the significance of virus detection deeply impacts human society. Viruses with genetic mutations are reported nearly every year, and people have prepared tools to detect the virus and vaccines to ensure proper treatments. Influenza virus (IV) is one of the most harmful viruses reporting various mutations, sub-types, and rapid infection speed for humans and animals including swine and poultry. Moreover, IV infection presents several harmful symptoms including cough, fever, diarrhea, chills, even causing death. To reduce the IV-induced harm, its proper and rapid detection is highly required. Conventional techniques were used against various IV sub-types including H1N1, H3N2, and H5N1. However, some of the techniques are time-consuming, expensive, or labor-intensive for detecting IV. Recently, the nucleic acid-based aptamer has gained attention as a novel bioprobe for constructing a biosensor. In this review, the authors discuss the recent progress in aptasensors for detecting IV in terms of an electrochemical and an optical biosensor.

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Rapid and background-free detection of avian influenza virus in opaque sample using NIR-to-NIR upconversion nanoparticle-based lateral flow immunoassay platform

Cited by 86 publications

References 32 publications

Detection of COVID-19: A review of the current literature and future perspectives

Detection of COVID-19: A review of the current literature and future perspectives

Lanthanide-Doped Upconversion Nanomaterials: Recent Advances and Applications

Recent Development of Aptasensor for Influenza Virus Detection

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