Rapid analytical method of 90Sr in urine sample: Rapid separation of Sr by phosphate co-precipitation and extraction chromatography, followed by determination by triple quadrupole inductively coupled plasma mass spectrometry (ICP-MS/MS)

Trends and Advances in Inductively Coupled Plasma Tandem Quadruple Mass Spectrometry (ICP-QMS/QMS) With Reaction Cell

“…Research fields and objectives. The research fields of the above references covered biology, 1-15 energy, 16 environment, 9,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] food/medical, 10-12,25-27,33-40 geology, 28,41-47 material, [48][49][50][51][52][53][54][55][56][57][58][59][60] and radionulide, 4,[22][23][61][62][63][64][65][66][67][68][69][70][71] respectively. In addition to these conventional elemental analysis topics, a study on the gas phase catalytic reaction has also been reported by using the reaction cell of ICP-QMS/QMS as the in-situ reaction field.…”

“…Many references used He, H2, O2, or NH3, which are usually included as the default cell gas for ICP-QMS/QMS. 4,22,26,44,46,[62][63][64][65][66] There are also multiple references using N2O, 3,23,28,45,68 CO2, 24,27,65 or CH4 43 as the cell gas to improve the separation of spectral interferences. For single element solution, the typical relative uncertainty of isotopic ratio obtained by ICP-QMS/QMS is roughly in the range from 0.1% to 0.2%, which is inferior to that can be achieved by multiple collector (MC-) ICP-MS by 3 to 4 orders of magnitude.…”

Novel 90Sr analysis of environmental samples by Ion-Laser InterAction Mass Spectrometry

“…1,13,16 Therefore, chemical separation and mass spectrometry combined should ideally be capable of separating 90 Zr by a factor >10 12 . Previous studies have reported LODs of <1 Bq (1 Bq ≈ 1.3 × 10 6 atoms) by ICP-MS/MS, 8,9 4 mBq by RIMS, 11 and <1 mBq by TIMS. 12,13 First studies in 90 Sr AMS reached LODs of 3 mBq, demonstrating the feasibility of 90 Sr AMS, but were limited by the intensity of the Zr-interference.…”

“…Therefore, the required abundance sensitivity ( 90 Sr/Sr atomic ratio) is at least 10 −11 for mass spectrometry. Published abundance sensitivity limits for various mass spectrometric techniques for 90 Sr are 10 −12 and 10 −9 in inductively coupled plasma tandem mass spectrometry (ICP-MS/MS), 8,9 10 −13 and 10 −10 in resonance ionization mass spectrometry (RIMS), 10,11 <2 × 10 −10 in thermal ionization mass spectrometry (TIMS) 12,13 and, prior to this work, <10 −13 in accelerator mass spectrometry (AMS). 14,15 While the theoretical abundance sensitivity of AMS is better than 10 −15 and should allow the detection of 90 Sr from the plenitude of stable Sr in any environmental matrix, it suffers like other mass spectrometric techniques from the interference of the stable isobar 90 Zr (in ICP-MS/MS, polyatomic ions also affect 90 Sr detection 8 ).…”

Ion-imprinted resin for use in an automated solid phase extraction system for determining 90Sr in environmental and human samples

“…However, to determine 90 Sr in such matrices is not an easy task, because the radiometric determination of a β-particle necessitates a complete isolation of the radionuclide before measurement because the β-particle is strongly absorbed into the matrix. Recently, several examples of 90 Sr determination by mass spectrometry were described [3][4][5], but none with a similar detection limit as the radiometric methods [6]. For samples with high Sr content such as teeth and bones, mass spectrometry cannot resolve the 88 Sr signal [7].…”