Abstract:Periodontitis is
a progressive inflammatory skeletal
disease characterized
by periodontal tissue destruction, alveolar bone resorption, and tooth
loss. Chronic inflammatory response and excessive osteoclastogenesis
play essential roles in periodontitis progression. Unfortunately,
the pathogenesis that contributes to periodontitis remains unclear.
As a specific inhibitor of the mTOR (mammalian/mechanistic target
of rapamycin) signaling pathway and the most common autophagy activator,
rapamycin plays a vital rol… Show more
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