Ranitidine

Drug–drug interaction between diclofenac, cetirizine and ranitidine

“…The UV spectra of 6.3 × 10 −5 M (1), 4.33 × 10 −5 M (2) and 5.7 × 10 −5 M (3) in ethanol (Table 1) showed characteristic bands and molar absorptivities, which were in agreement with previous studies [4,10,11]. A very slight, negligible, hypsochromic shift occurred on buffering 1 with acid or alkali.…”

“…It is a histamine H 2 -receptor antagonist with a furan ring structure that increases its potency to inhibit gastric acid secretion induced by various stimuli, while lacking the anti-androgenic and hepatic microsomal enzyme inhibiting effects [3]. IR analysis confirmed 3 to being a tautomer, with the enol form dominating [4]; as follows: The question of whether or not these three drugs may interact was the basis of this study. Kamath et al [5] stated that paracetamol interfered with the determination of diclofenac sodium studied by flow-injection analysis.…”

“…Ranitidine has two broad bands with absorbance maxima at about 325 and 230.4 nm. The first band is characteristic of the nitro group olefin conjugation [4]. The second band is assigned to the -* transition within the furan ring.…”

An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique

“…Monographs in the "Analytical Profile of Drug Substances" series were also published for diltiazem [11], cimetidine [12], and ranitidine [13]. Eur Ph 2002 [14] recommends an HPLC assay for diltiazem in its dosage forms.…”

Improving the filterability and solid density of ranitidine hydrochloride form 1

“…RAN‐HCl works by blocking histamine H 2 receptor in the gut 1. The chemical formula of RAN‐HCl is C 13 H 22 N 4 O 3 S · HCl and the structure of one of the possible tautomers is shown in Scheme 2…”