Range-gated pulsed Doppler ultrasonographic evaluation of carotid arterial blood flow in small preterm infants with patent ductus arteriosus

Wilcox, W.D.; Carrigan, Timothy A.; Dooley, Kenneth J.; Giddens, Don P.; Dykes, Francine D.; Lazzara, Anthony; Ray, Judith; Ahmann, Peter A.

doi:10.1016/s0022-3476(83)80546-0

Cited by 30 publications

(10 citation statements)

References 14 publications

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“…In 1981, Perlman et al 15 demonstrated reduced diastolic flow in the anterior cerebral arteries in premature babies with ductus arteriosus. Wilcox et al 16 reported their Doppler findings in the carotid arteries in 23 infants with PDA. They found that pandiastolic or late-diastolic reversal of flow in the carotid artery was associated with large or small ductus, respectively.…”

Section: Discussionmentioning

confidence: 98%

Abnormal renal and splanchnic arterial Doppler pattern in premature babies with symptomatic patent ductus arteriosus.

Wong

Hui

1990

Journal of Ultrasound in Medicine

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The flow velocity pattern in the descending aorta, renal arteries, and celiac and superior mesenteric arteries was studied with pulsed Doppler in eight premature babies with symptomatic ductus arteriosus before and after ductal closure, as compared to nine premature babies without ductus arteriosus. There was a decrease or reversal of flow in diastole in the above arteries in babies with ductus and diastolic flow reappeared after ductal closure. This diastolic steal phenomenon has not been previously demonstrated in the abdominal arteries. It may contribute to proneness to ischemic damage of abdominal organs in premature babies.

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Section: Discussionmentioning

confidence: 98%

Abnormal renal and splanchnic arterial Doppler pattern in premature babies with symptomatic patent ductus arteriosus.

Wong

Hui

1990

Journal of Ultrasound in Medicine

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“…This is mainly due to the inability to maintain adequate diastolic perfusion through the capillary bed. A compensatory increase in systolic perfusion may take place, although this is probably not very effective as judged by the relatively normal systolic blood pressure and systolic blood flow velocity found in infants with PDA (7,22). Furthermore, the high pulsatility of the cerebral blood flow may be hazardous to the fragile periventricular capillaries, with risk for rupture and intraventricular hemorrhage (9).…”

Section: T O Fmentioning

confidence: 99%

“…Infants with large ductal shunts show flow patterns in the large systemic arteries suggesting low, absent or even reversed diastolic flow (6,7). Studies of intracranial arterial flow patterns indicate a poor antegrade flow in diastole, improving after ductus closure (8,9).…”

mentioning

confidence: 99%

Ductus Closure in Preterm Infants Effects on Cerebral Hemodynamics

1986

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ABSTRACT. Idracranial arterial blood flow velocities were studied before and after ductus closure by smgery (n=8) and indomethacin (n=10) in very low birth weight infants. Blood flow velocities were measured non‐invasively through the fontanel with a pulsed Doppler velocimeter. Ligation of the ductus was associated with a 62% increase in mean flow velocity 24 hours after surgery, mainly secondary to increased diastolic flow velocity. Iodomethacin (0.2 nig/kg i.v.) induction of ductus constriction was associated with a 36% decrease of mean flow velocity one hour after administration. At 24 hours, the intracranial blood flow velocity had returned to the pretreatment level but was still significantly lower than after ligation. Ductus dosure is associated with marked changes in cerebral hemodynamics. Ligation causes increased arterial blood flow velocities and indomethacin administration seems to reduce Mood flow velocities to the brain.

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“…Doppler ultrasonography of cerebral arteries in preterm infants with a large patent ductus arteriosus (PDA) has been reported to show a decreased and sometimes retrograde diastolic blood flow [5,8,16]. These alterations might lead to cerebral ischaemia [10,11] and an increased probability of necrotizing enterocolitis (NEC) or renal failure [3,9].…”

Section: Introductionmentioning

confidence: 99%

Abnormal blood flow patterns in renal arteries of small preterm infants with patent ductus arteriosus detected by Doppler ultrasonography

Bömelburg

Jorch

1989

Eur J Pediatr

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Blood flow velocities and pulsatory indices in both renal arteries (RAs) and in the internal carotid artery (CAI) were measured by pulsed Doppler ultrasonography in ten preterm infants with patent ductus arteriosus (PDA), before and after surgical ligation. The results obtained in the RAs were compared to those found in a reference group of 22 stable preterm infants. In the RAs the diastolic steal volume of the PDA led to a marked decrease in diastolic blood flow velocity (range 3 to -23 cm/s). Seven infants showed retrograde diastolic flow, whereas only three infants had these flow patterns in the CAI. In the RAs, the peak systolic blood flow velocities (range 56 to 135 cm/s) exceeded the values found in the reference group by 85% on average. The pulsatility indices reached values of above 1,00. In spite of the increase in systolic flow velocities before surgery, the time mean of maximum velocities was significantly lower than those measured after surgery and in the reference group. After PDA ligation, blood flow velocities normalized. The present study shows that a large PDA may induce abnormal flow patterns even in the RAs. These flow patterns may predispose to renal hypoperfusion and subsequent impairment of renal function.

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Range-gated pulsed Doppler ultrasonographic evaluation of carotid arterial blood flow in small preterm infants with patent ductus arteriosus

Cited by 30 publications

References 14 publications

Abnormal renal and splanchnic arterial Doppler pattern in premature babies with symptomatic patent ductus arteriosus.

Abnormal renal and splanchnic arterial Doppler pattern in premature babies with symptomatic patent ductus arteriosus.

Ductus Closure in Preterm Infants Effects on Cerebral Hemodynamics

Abnormal blood flow patterns in renal arteries of small preterm infants with patent ductus arteriosus detected by Doppler ultrasonography

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