Randomized Trial of Supervised Versus Unsupervised Optokinetic Exercise in Persons With Peripheral Vestibular Disorders

Pavlou, Marousa; Bronstein, Adolfo M.; Davies, Rosalyn

doi:10.1177/1545968312461715

Cited by 73 publications

(95 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, apart from extending the current results, future studies should focus on the implication of these findings for therapeutic options in VID patients. It has already been shown that rehabilitation programmes by means of optokinetic stimulation are beneficial for these patients (Pavlou et al, 2011, Pavlou et al, 2013). In addition, it should be investigated whether VID patients could potentially benefit from e.g.…”

Section: Discussionmentioning

confidence: 99%

Altered functional brain connectivity in patients with visually induced dizziness

Ombergen

Heine²,

Jillings

et al. 2017

NeuroImage: Clinical

View full text Add to dashboard Cite

BackgroundVestibular patients occasionally report aggravation or triggering of their symptoms by visual stimuli, which is called visually induced dizziness (VID). These patients therefore experience dizziness, discomfort, disorientation and postural unsteadiness. The underlying pathophysiology of VID is still poorly understood.ObjectiveThe aim of the current explorative study was to gain a first insight in the underlying neural aspects of VID.MethodsWe included 10 VID patients and 10 healthy matched controls, all of which underwent a resting state fMRI scan session. Changes in functional connectivity were explored by means of the intrinsic connectivity contrast (ICC). Seed-based analysis was subsequently performed in visual and vestibular seeds.ResultsWe found a decreased functional connectivity in the right central operculum (superior temporal gyrus), as well as increased functional connectivity in the occipital pole in VID patients as compared to controls in a hypothesis-free analysis. A weaker functional connectivity between the thalamus and most of the right putamen was measured in VID patients in comparison to controls in a seed-based analysis. Furthermore, also by means of a seed-based analysis, a decreased functional connectivity between the visual associative area and the left parahippocampal gyrus was found in VID patients. Additionally, we found increased functional connectivity between thalamus and occipital and cerebellar areas in the VID patients, as well as between the associative visual cortex and both middle frontal gyrus and precuneus.ConclusionsWe found alterations in the visual and vestibular cortical network in VID patients that could underlie the typical VID symptoms such as a worsening of their vestibular symptoms when being exposed to challenging visual stimuli. These preliminary findings provide the first insights into the underlying functional brain connectivity in VID patients. Future studies should extend these findings by employing larger sample sizes, by investigating specific task-based paradigms in these patients and by exploring the implications for treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Altered functional brain connectivity in patients with visually induced dizziness

Ombergen

Heine²,

Jillings

et al. 2017

NeuroImage: Clinical

View full text Add to dashboard Cite

show abstract

“…Optokinetic stimulation may be effective in acute stroke patients as it is used for balance system treat-ment in vestibular rehabilitation (Pavlou, 2010;Pavlou, Bronstein, & Davies, 2013). Balance is a pre-requisite to function (Mercier, Audet Hebert, Rochette, & Dubois, 2001;Yavuzer, Eser, Karakus, Karaoglan, & Stam, 2006).…”

Section: Discussionmentioning

confidence: 99%

Does use of the optokinetic chart stimulation based OKCSIB protocol improve recovery of upper and lower limb movements, function and quality of life at 3 year follow up in dense strokes? A retrospective case control series

Chitambira

2014

NRE

View full text Add to dashboard Cite

BACKGROUND AND OBJECTIVE:The aim was to compare follow up impairment, function and quality of life outcomes between dense parietal centred strokes treated by the optokinetic chart based OKCSIB protocol and those treated by conventional neuro-physiotherapy. DESIGN AND SETTING: Follow up retrospective case control series in the community. METHOD AND MATERIALS: 643 persons with stroke were eligible for initial screening to see if they met inclusion criteria. Only 37 potential participants were eligible, with 18 of them still alive. From the 18 only 8 consented to participate in the follow up study. RESULTS: Sixteen mortalities that occurred post discharge were all from the conventional group. The OKCSIB group had statistically significant improved upper limb STREAM scores (p < 0.05). The OKCSIB group had statistically significant reduction in hand spasticity with none of the OKCSIB participants developing hand spasticity (p < 0.05). The OKCSIB group also had better lower limb STREAM scores although these were not statistically significant (p > 0.05). Barthel Index, and quality of Life improvements were non-significant (p > 0.05). CONCLUSION: The OKCSIB protocol led to better recovery of voluntary movements at 3 year follow up. However lack of randomisation and the small number of participants, necessitate further research to be carried out.

show abstract

“…10−12 It is believed that graded exposure to optokinetic stimulation reduces the abnormal overreliance on visual input for perceptual and postural responses, 6,13 with recent findings showing that short-term repeated exposure to visuo-vestibular exercises induces adaptive changes, thereby decreasing (improving) the magnitude of visual dependency in healthy controls. 13 The degree of VV symptom improvement varies among individuals 11,14 and a subset of patients do not report a pre-/posttreatment change. 14 The primary aim of this study was to compare the presence and severity of VV symptoms at baseline and pre-/ posttreatment VV score changes in people with refractory vestibular symptoms with and without a binocular vision abnormality.…”

Section: Introductionmentioning

confidence: 99%

Effect of Developmental Binocular Vision Abnormalities on Visual Vertigo Symptoms and Treatment Outcome

Pavlou

Acheson

Nicolaou

et al. 2015

Journal of Neurologic Physical Therapy

Self Cite

View full text Add to dashboard Cite

show abstract

Randomized Trial of Supervised Versus Unsupervised Optokinetic Exercise in Persons With Peripheral Vestibular Disorders

Abstract: The DVD may be an effective and economical method of integrating OK into VR. However, rehabilitation should be supervised for greater compliance and improvements, particularly for postural stability and psychological state.

Cited by 73 publications

References 54 publications

Altered functional brain connectivity in patients with visually induced dizziness

Altered functional brain connectivity in patients with visually induced dizziness

Does use of the optokinetic chart stimulation based OKCSIB protocol improve recovery of upper and lower limb movements, function and quality of life at 3 year follow up in dense strokes? A retrospective case control series

Effect of Developmental Binocular Vision Abnormalities on Visual Vertigo Symptoms and Treatment Outcome

Contact Info

Product

Resources

About