2002
DOI: 10.1067/mtc.2002.121048
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Randomized trial comparing partial versus complete chordal-sparing mitral valve replacement: Effects on left ventricular volume and function

Abstract: Complete retention of the mitral subvalvular apparatus during mitral valve replacement confers a significant early advantage by reducing left ventricular chamber size and systolic afterload compared with partial chordal preservation. Furthermore, left ventricular ejection performance continues to improve over time, probably because of more favorable left ventricular remodeling.

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Cited by 118 publications
(80 citation statements)
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“…1 This subvalvular apparatus performs a dual role, both maintaining valvular competence and enhancing left ventricular (LV) systolic pump function. The importance of mitral papillary-annular continuity for optimal global LV systolic performance, a concept we have previously termed "valvular-ventricular interaction," 2 has been demonstrated in clinical studies showing improved patient outcomes and LV performance after chordal preservation during mitral valve replacement 3,4 and in experimental studies documenting global LV contractile dysfunction after transection of all chordae. 2,5 Mitral valve repair is associated with superior survival and improved LV function compared with replacement, 6,7 in part because the entire subvalvular apparatus is preserved.…”
mentioning
confidence: 99%
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“…1 This subvalvular apparatus performs a dual role, both maintaining valvular competence and enhancing left ventricular (LV) systolic pump function. The importance of mitral papillary-annular continuity for optimal global LV systolic performance, a concept we have previously termed "valvular-ventricular interaction," 2 has been demonstrated in clinical studies showing improved patient outcomes and LV performance after chordal preservation during mitral valve replacement 3,4 and in experimental studies documenting global LV contractile dysfunction after transection of all chordae. 2,5 Mitral valve repair is associated with superior survival and improved LV function compared with replacement, 6,7 in part because the entire subvalvular apparatus is preserved.…”
mentioning
confidence: 99%
“…2,5 Mitral valve repair is associated with superior survival and improved LV function compared with replacement, 6,7 in part because the entire subvalvular apparatus is preserved. 4 Although the importance of chordal preservation for LV systolic function during valve replacement is widely accepted, the selective roles of first-order versus second-order chordae have only recently been explored. In a study of isolated porcine hearts, Obadia et al showed that transection of the first-order chordae resulted in leaflet prolapse and mitral regurgitation (MR) without affecting circumferential segmental shortening along the mid-anterolateral LV wall.…”
mentioning
confidence: 99%
“…1A) when all the chordate tendinae are severed [1,2]. Mitral valve repair is associated with a higher survival and better left ventricular function compared to prostheses implantation in part due to the preservation of MSVA [3]. However, mitral valve repair techniques are not always feasible or indicated, leading to mitral valve replacement, mainly in the cases of impairment due to fibrosis or calcification.…”
Section: Introductionmentioning
confidence: 99%
“…6) Preservation of the leaflets and subvalvular apparatus are generally recommended to improve short-term and long-term outcomes in mitral valve replacement. 7,8) However, it is not always a possible procedure.…”
Section: Introductionmentioning
confidence: 99%