Randomized double-blind study of prophylactic methenamine hippurate treatment of patients with indwelling catheters

Norberg, Astrid; Norberg, Bo; Parkhede, Ulf; Gippert, Hans; Lundbeck, Kari

doi:10.1007/bf00874662

Cited by 17 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The use of indwelling catheters in the management of aged patients with urinary' incontinence is associated with a non-controllable nosocomial situation [7,15,16]. It is suggested that catheters be replaced by diapers whenever possible.…”

Section: Discussionmentioning

confidence: 99%

“…First, antibiotics were re placed by methenamine hippurate, which has no ecological side effects. The function time of silicone-coated latex catheters was dou bled during treatment with methenamine hippurate but bacteriuria and pyuria per sisted [15,16], Then an attempt was made to make latex catheters bactericidal by coating with copper metal; the attempt has, however, not been a clinical success hitherto [17],…”

Section: Discussionmentioning

confidence: 99%

“…It was derived from studies on the problems of patients with indwelling cathe ters [15,16]. One basic problem with in dwelling catheters is that they introduce a massive persistent bacteriuria and pyuria in the urinary tract.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The Urine Smell around Patients with Urinary Incontinence

Sandström¹,

Norberg²,

Eriksson³

et al. 1984

Gerontology

View full text Add to dashboard Cite

The foul smell of urine around patients with urine incontinence is thought to be due mainly to the production of ammonia from urea by bacterial ureases. The production of ammonia was thus measured by infrared spectrophotometry in control diapers and in test diapers impregnated with copper acetate (CA), after use by urine-incontinent patients with persistent bacteriuria. The CA-impregnated diapers produced significantly less ammonia than the control diapers. The CA-impregnated diapers were not bactericidal, however. The results are consistent with the hypothesis that the smell reduction of the CA-impregnated diapers is due to a bacteriostatic action or an inhibition of bacterial ureases by CA.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Urine Smell around Patients with Urinary Incontinence

Sandström¹,

Norberg²,

Eriksson³

et al. 1984

Gerontology

View full text Add to dashboard Cite

show abstract

“…Previously, chemotherapeutic agents were used against catheter-induced bacteriuria, but these had only a transient effect on catheter-induced bacteriuria (1, 2, 3). In addition, the patient's endogenous bacterical flora was profoundly disturbed, with selection of multiresistant opportunistic strains of bacteria (1,2,3).…”

mentioning

confidence: 99%

Urinary Tract Infection After Vaginal Surgery: Effect of prophylactic treatment with methenamine hippurate

Tyreman¹,

Andersson²,

Kroon³

et al. 1986

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

One hundred and nine consecutive patients undergoing surgery for uterovaginal prolapse followed by indwelling urinary catheter for 3 days were randomized for prophylactic treatment with methenamine hippurate (MH) or no MH prophylaxis. Significantly less bacteriuria occurred in the MH-treated patient group. In particular, the opportunistic hospital flora appeared to be suppressed by MH treatment. It is suggested that MH prophylaxis, 1 g three times daily, be used in gynecological surgery followed by short-term urinary catheterization.

show abstract