Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand

Brosseau, Lucie; Wells, George A.; Marchand, Serge; Gaboury, Isabelle; Stokes, Barbara; Morin, Mario; Casimiro, Lynn; Yonge, Katharine; Tugwell, Peter

doi:10.1002/lsm.20137

Cited by 85 publications

(100 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They found that there were no significant differences in pain quality between the active treatment group and the control group. 40 This may be attributed to differences in nature of arthritic changes and number of sessions of treatment. 40 Another different factor for contrast is the difference between the gallium-aluminum-arsenide diode laser used in their work 40 and the gallium-arsenide diode laser used in this study.…”

Section: Discussionmentioning

confidence: 99%

“…40 This may be attributed to differences in nature of arthritic changes and number of sessions of treatment. 40 Another different factor for contrast is the difference between the gallium-aluminum-arsenide diode laser used in their work 40 and the gallium-arsenide diode laser used in this study. The contradictions in the literature of LLLT benefits may be attributed to variations in treatment parameters by LLLT, such as wavelength, power, energy density, number, and duration of treatment, size of exposure area, and method Laser Therapy on Chronic Knee Osteoarthritis of Elders of laser administration.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

2016

View full text Add to dashboard Cite

Introduction: Osteoarthritis (OA) is a common degenerative joint disease particularly in older subjects. It is usually associated with pain, restricted range of motion, muscle weakness, difficulties in daily living activities and impaired quality of life. To determine the effects of adding two different intensities of low-level laser therapy (LLLT) to exercise training program on pain severity, joint stiffness, physical function, isometric muscle strength, range of motion of the knee, and quality of life in older subjects with knee OA. Methods: Patients were randomly assigned into three groups. They received 16 sessions, 2 sessions/week for 8 weeks. Group-I: 18 patients were treated with a laser dose of 6 J/cm 2 with a total dose of 48 J. Group-II: 18 patients were treated with a laser dose of 3 J/cm 2 with a total dose of 27 J. Group-III: 15 patients were treated with laser without emission as a placebo. All patients received same exercise training program including stretching and strengthening exercises. Patients were evaluated before and after intervention by visual analogue scale (VAS), the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index for quality of life, handheld dynamometer and universal goniometer. Results: T test revealed that there was a significant reduction in VAS and pain intensity, an increase in isometric muscle strength and range of motion of the knee as well as increase in physical functional ability in three treatment groups. Also analysis of variance (ANOVA) proved significant differences among them and the post hoc tests (LSD) test showed the best improvements for patients of the first group. Conclusion: It can be concluded that addition of LLLT to exercise training program is more effective than exercise training alone in the treatment of older patients with chronic knee OA and the rate of improvement may be dose dependent, as with 6 J/cm 2 or 3 J/cm 2 .

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

2016

View full text Add to dashboard Cite

show abstract

“…Several progressive and degenerative diseases have been effectively treated by means of LLLT (12,38,39) , but there is controversy regarding the results from studies analyzing pain and function among patients with knee OA, mainly because of the variations in the methods used. In the present clinical trial, care was taken to follow the WALT recommendations (40) regarding how to conduct a clinical trial with LLLT, and care was taken to report all the parameters used in the study.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, it has an analgesic effect, although the mechanisms through which this occurs remain uncertain. The suggested mechanisms include: increased mitochondrial ATP and tissue oxygenation, increased levels of neurotransmitters implicated in pain modulation (such as serotonin) and anti-inflammatory effects (5,12) .…”

mentioning

confidence: 99%

Eficácia a curto prazo do laser de baixa intensidade em pacientes com osteoartrite do joelho: ensaio clínico aleatório, placebo-controlado e duplo-cego

Fukuda¹,

Fukuda²,

Guimarães³

et al. 2011

Rev. bras. ortop.

View full text Add to dashboard Cite

Objective: This study was designed to evaluate the short-term efficacy of low-level laser therapy (LLLT) for improving pain and function in patients with knee osteoarthritis. Methods: Forty-seven patients with knee osteoarthritis (79 knees), of both genders, participated in this randomized controlled double-blind clinical trial. They were randomly allocated to two groups: laser group with 25 patients (41 knees) and placebo group with 22 patients (38 knees). LLLT was performed three times a week, totaling nine sessions, using a AsGa 904 nm laser with mean power of 60 mW and beam area of 0.5 cm 2 . Nine points were irradiated on the knee, with energy of 3.0 J/point. The placebo group was treated with the same laser device, but with a sealed probe. Evaluations using Lequesne, visual numerical scale (VNS), Timed Up and Go (TUG), goniometry and dynamometry were conducted before the treatment started and after the nine sessions of LLLT. Results: A significant improvement in pain and function was found in all the assessments applied to the laser group. On comparing the laser group with the placebo group, significant differences were found in the VNS-resting and Lequesne evaluations. Conclusion: Treatment with LLLT improves pain and function over the short term in patients with knee osteoarthritis.

show abstract

“…Other authors have written more extensively on this topic. 9,18,19 The primary purpose of this article was to present a case of MCP joint OA associated with a manual labor occupation and, in doing so, familiarize chiropractors with the so-called Missouri metacarpal syndrome. 15 This article also serves to remind the chiropractic physician of the key differentials of MCP arthropathy, namely, hemochromatosis and CPPD crystal deposition disease.…”

Section: Discussionmentioning

confidence: 99%

Manual labor metacarpophalangeal arthropathy in a truck driver: a case report

Emary¹

2010

Journal of Chiropractic Medicine

View full text Add to dashboard Cite

Objective: The purpose of this study is to present an unusual and rarely described case of occupational hand arthropathy involving the metacarpophalangeal (MCP) joints. Clinical Features: A 62-year-old male truck driver (of 35 years) presented to a chiropractic clinic with pain and stiffness along the third metacarpal and MCP joint of the left hand. Examination revealed severe pain and limited flexion at the third MCP joint. Bilateral radiographs demonstrated severe osteoarthritis (OA) of this joint in the left (nondominant) hand and mild-to-moderate (asymptomatic) OA in the same joint on the right. Results of laboratory blood tests were unremarkable for metabolic, inflammatory, or infectious joint disease. Intervention and Outcome: The patient was diagnosed with bilateral, third MCP joint OA associated with manual labor. He was treated unsuccessfully with a short course of low-level laser therapy, MCP joint mobilization, and hand-stretching exercises. After 3½ years, the patient continues to work despite ongoing and worsening symptoms. Three serial left hand radiographs are presented, highlighting the progressive nature of this arthropathy. Conclusion: The differential diagnosis in patients presenting with manual labor MCP joint OA should include hemochromatosis and calcium pyrophosphate dihydrate crystal deposition disease. Because of the increased risk of serious systemic disease, it is imperative that these latter 2 disorders are ruled out before the former is diagnosed.

show abstract

Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand

Abstract: LLLT is no better than placebo at reducing pain, morning stiffness, or improving functional status for OA-hand patients.

Cited by 85 publications

References 34 publications

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

Eficácia a curto prazo do laser de baixa intensidade em pacientes com osteoartrite do joelho: ensaio clínico aleatório, placebo-controlado e duplo-cego

Manual labor metacarpophalangeal arthropathy in a truck driver: a case report

Contact Info

Product

Resources

About