Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus

Screening the nose, throat and the naso-pharynx for methicillin-resistant Staphylococcus aureus: a pilot study

“…Multi-site MRSA carriage impedes nasal decolonisation (Harbarth et al, 2000). Previous findings from a nasal decolonisation randomised controlled trial we undertook reported short-term nasal decolonisation success rates of 50% (Poovelikunnel et al, 2017) similar to other studies (Harbarth et al, 1999). The present study demonstrates that most nasally colonised patients (80%) are also colonised in the throat/oral cavity.…”

Antibacterial potential of Swiss honeys and characterisation of their bee‐derived bioactive compounds

“…Honey is considered to be a functional food and currently has gained much attention because of its positive biological and health properties. Numerous randomised controlled clinical studies have provided compelling evidence that honey possesses antibacterial/antibiofilm, antiviral and anti‐inflammatory properties when applied topically. One of the important and the most studied effects of honey is its antibacterial activity.…”

Egyptian fennel honey and/or propolis against MRSA harboring both mecA & icaAgenes

“…S. aureus is highly sensitive either to honey 44 or EEP 45 than other Gram positive and Gram-negative bacteria. In vitro antimicrobial honey activity against MRSA [11][12][13][14][15][16][17][18][19][20][21] with wide varied potencies of MIC ranging from 3.1 up to 25% or inhibition zone 20,46,47 of 8-28mm. These differences are depending on botanical, geographical and seasonal conditions 48 leading to differences in antimicrobial potency more than 100-fold in-between different honeys.…”

“…10 So, searching for antimicrobial agent that fights biofilm production is of great concern. Against MRSA, not only honey [11][12][13][14][15][16][17][18][19][20][21] or propolis [22][23][24][25][26][27] has antimicrobial activities, but also they have tremendous antibiofilm activities [28][29][30][31] which are widely studied and documented. Since Egyptian fennel honey has potent antimicrobial activity against S. aureus, [32][33][34] the study aimed to study the antimicrobial activity of Egyptian fennel honey and/or propolis against these stubborn biofilm producing MRSA recovered from food and food workers.…”