Randomized Controlled Trial of Bisacodyl Suppository Versus Placebo for Postoperative Ileus After Elective Colectomy for Colon Cancer

Wiriyakosol, Sukanya; Kongdan, Youwanuch; Euanorasetr, Chakrapan; Wacharachaisurapol, Noppadol; Lertsithichai, Panuwat

doi:10.1016/s1015-9584(08)60017-2

Cited by 21 publications

(24 citation statements)

References 19 publications

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“…Abdominal distention and postoperative ileus can often inhibit the TBI patient from reaching their EN goal. Initiating aggressive bowel regimens with twice daily liquid stool softeners and rectal laxative stimulants upon initiation of EN may abate this complication 89 …”

Section: Facilitating Enteral Nutrition Tolerancementioning

confidence: 99%

“…Initiating aggressive bowel regimens with twice daily liquid stool softeners and rectal laxative stimulants upon initiation of EN may abate this complication. 89 Diarrhea can be one of the most frustrating and common EN intolerance for nursing staff and other care-givers. Diarrhea is infrequent in the first few days of the acute TBI.…”

Section: Facilitating Enteral Nutrition Tolerancementioning

confidence: 99%

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Nutrition Considerations in Traumatic Brain Injury

2008

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The provision of adequate nutrition support for patients with traumatic brain injury (TBI) has been a clinical challenge for decades. The primary and secondary injuries create unique metabolic derangements along with accompanying issues such as optimal timing and route of nutrition, appropriate fluid and electrolytes, drug administration, rehabilitation, and dysphagia. Enteral nutrition is clearly established as the preferential route of nutrition support for this population vs parenteral nutrition. There appears to be a consensus on early initiation of enteral nutrition, but less definitive are recommendations on advancement timing and formula components. Nutrition therapies should include exact fluid resuscitation goals specific for TBI and strict electrolyte monitoring to avoid extreme fluid, electrolyte, or glucose shifts that could be detrimental to the patient. While the critical care patient often tolerates small bowel feeding, the long-term rehabilitation patient should transition to and tolerate gastric feeding. Drug-nutrient and adverse drug reactions such as diarrhea should be routinely evaluated in patients receiving enteral nutrition. Monitoring for dysphagia is critical to avoid the costly negative aspects associated with aspiration and to capitalize on quality of life and appropriate oral nutrition. Emphasizing the priority of early nutrition support within a multi-disciplinary team may be the critical key for successful provision and tolerance of nutrition support in the TBI population.

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Section: Facilitating Enteral Nutrition Tolerancementioning

confidence: 99%

Section: Facilitating Enteral Nutrition Tolerancementioning

confidence: 99%

Nutrition Considerations in Traumatic Brain Injury

2008

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“…With regard to postoperative ileus, if the role of epidural analgesia certainly accelerates the recovery of bowel function after open abdominal surgery, its role after laparoscopic surgeries is still controversial [281]. Positive results have been reported on the duration of postoperative ileus with the use of laxatives such as milk of magnesia and bisacodyl [272,307]. Prokinetic like metclopramide are not effective.…”

Section: Prevention Of Postoperative Ileusmentioning

confidence: 99%

Anesthetic and Adjunctive Drugs for Fast-Track Surgery

Baldini¹,

Carli²

2009

CDT

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With the changes in health care dictated by economic pressure, there has been a realization that hospital stay could be shortened without compromising quality of care. Advances in surgical technology and anesthetic drugs have made an impact in the way perioperative care is delivered with some emphasis on multidisciplinary approach. From the expansion of ambulatory care, lessons were learnt how to apply same concepts to major surgery with the understanding that interventions to attenuate the surgical stress would facilitate the return to "baseline". Beside minimal invasive approach to surgery, anesthesia interventions are arranged with the intent to decrease the negative effects of surgical stress and pain, to minimize the side effects of drugs and at the same time to facilitate the recuperation which follows after surgery. Fast-track or accelerated care encompasses many aspects of anesthesia care, not only preoperative preparation and prehabilitation, but intraoperative attenuation of surgical stress and postoperative rehabilitation. The anesthesiologist is part of this team with the specific mission to use medications and techniques which have the least side effects on organ functions, provide analgesia which in turn facilitates the intake of food and mobilization out of bed. This chapter has been conceived with the intention to direct the clinician towards procedure-specific protocols where the choice of medications and techniques is based on published evidence. The success of implementing fast-track depends more on dynamic harmony amongst the various participants (surgeons, anesthesiologists, nurses, nutrtionists, physiotherapists) than on reaching an optimum level of excellence at each separate organization level.

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“…Mittels Eisensupplementation konnte das Hämoglobin zum Operationszeitpunkt angehoben werden ( Der postoperative Ileus (POI) ist ein häufiger und bedrohlicher Zustand. In einer randomisierten Untersuchung wurde der Effekt von Bisacodylsuppositorien untersucht [53]. 20 Patienten erhielten am 3.…”

Section: Perioperative Aspekteunclassified

Chirurgie des kolorektalen Karzinoms

Runkel

2009

Coloproctol

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Randomized Controlled Trial of Bisacodyl Suppository Versus Placebo for Postoperative Ileus After Elective Colectomy for Colon Cancer

Abstract: Bisacodyl suppository seems to be effective and safe in resolving postoperative ileus after elective colectomy in colon cancer patients.

Cited by 21 publications

References 19 publications

Nutrition Considerations in Traumatic Brain Injury

Nutrition Considerations in Traumatic Brain Injury

Anesthetic and Adjunctive Drugs for Fast-Track Surgery

Chirurgie des kolorektalen Karzinoms

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