Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing

Osther, Palle Jørn Sloth; Gjøde, P; Mortensen, Bettina; Mortensen, P.B.; Bartholin, J; Gottrup, Finn

doi:10.1002/bjs.1800820824

Cited by 70 publications

(36 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Four complications were unrelated to the laparoscopic technique. Three were wound infections (2.5%), which compares favorably with results obtained in conventional colonic operations [4,15,19,21,22]. The necessary ingredients of wound infection are contamination with pathogenic organisms and a susceptible host.…”

Section: Discussionsupporting

confidence: 57%

Postoperative complications of laparoscopic-assisted colectomy

et al. 1997

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 57%

Postoperative complications of laparoscopic-assisted colectomy

et al. 1997

View full text Add to dashboard Cite

show abstract

“…The monofilament poliglecaprone 25 produced significantly narrower scars than polyglactin 910. Osther et al [9] in a randomized control trial compared polyglycolic acid and monofilament polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing. Wound infection demanding surgical intervention was found in 7 % of patients with polyglyconate and 16 % with polyglycolic acid sutures (P 0.04).…”

Section: Discussionmentioning

confidence: 99%

Comparison of Efficacy of Three Suture Materials, i.e., Poliglecaprone 25, Polyglactin 910, Polyamide, as Subcuticular Skin Stitches in Post-Cesarean Women: A Randomized Clinical Trial

Vats¹,

Suchitra

2013

J Obstet Gynecol India

View full text Add to dashboard Cite

Objectives To compare the efficacy of three suture materials, i.e., poliglecaprone 25, polyglactin 910, and polyamide, as subcuticular skin stitches in post-cesarean women. Study Design This was a randomized clinical trial. Population The study was conducted in the department of obstetrics and gynecology of a tertiary institute, LTMMC, Sion, Mumbai, India. Only those women undergoing emergency cesarean section were included. Methods The study was conducted in the department of obstetrics and gynecology of a tertiary institute, LTMMC, Sion, Mumbai, India. 90 women undergoing emergency cesarean section were included and divided into three groups. In group 1, poliglecaprone 25 was used as subcuticular skin stitches; in group 2, polyglactin 910 was used as subcuticular skin stitches; and in group 3, polyamide was used as subcuticular skin stitches. Results Thirty percentage of the patients in group 3 had discomfort on day 10, while it was only 3.3 % in group 1. In group 1, 6.6 % patients had swelling and indurations, while it was 33.3 % in group 2 on day 4. Wound dehiscence was present in 3.3 % patients in group 1, 26.6 % in group 2, and 6.6 % in group 3. Regarding wound healing, 93.3 % patients had excellent wound healing in group 1, 66.6 % in group 2, and 86.6 % in group 3. Conclusions The results were almost similar with poliglecaprone and polyamide, except for discomfort which was present more in patients in group 3.

show abstract

“…1 The most prominent polymers for this indication are polyesters such as polyglycolic acid (polyglycolide [PGA]) and polylactic acid (polylactide [PLA]). They have found widespread use in clinical medicine for bone fixation, 2 as surgical suture, 3 as scaffold for tissue engineering, [4][5][6] and for controlled drug release. 7 They have also been proposed as bone substitution material.…”

Section: Introductionmentioning

confidence: 99%

Biologically and chemically optimized composites of carbonated apatite and polyglycolide as bone substitution materials

Linhart

Peters²,

Lehmann

et al. 2000

J. Biomed. Mater. Res.

169

View full text Add to dashboard Cite

We report on the development and characterization of a new composite material consisting of amorphous carbonated apatite, Ca(5)(PO(4), CO(3))(3)(OH), and microstructured poly(hydroxyacetic acid), polyglycolide (PGA). This material is able to keep the pH of a surrounding solution within the physiological range (7.2-7.6). This was achieved by chemical fine-tuning of the counterplay between the acidic degradation of the polyester and the basic dissolution of calcium phosphate. Microporous samples with pore sizes of <1 microm and compact samples were prepared. The biological behavior was assayed in vitro by long-term osteoblast culture. Morphological and biochemical analyses of cell differentiation revealed excellent biocompatibility, leading to cell attachment, collagen and osteocalcin expression, and mineral deposition. This material could be of use as a biodegradable bone substitution material and as a scaffold for tissue engineering.

show abstract

Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing

Cited by 70 publications

References 11 publications

Postoperative complications of laparoscopic-assisted colectomy

Postoperative complications of laparoscopic-assisted colectomy

Comparison of Efficacy of Three Suture Materials, i.e., Poliglecaprone 25, Polyglactin 910, Polyamide, as Subcuticular Skin Stitches in Post-Cesarean Women: A Randomized Clinical Trial

Biologically and chemically optimized composites of carbonated apatite and polyglycolide as bone substitution materials

Contact Info

Product

Resources

About