Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: A report from the Children's Oncology Group

Abstract

Background To reduce the risk of adjustment problems associated with Hematopoietic Stem Cell Transplant (HSCT) for adolescents/young adults (AYA), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: (a) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; (b) decrease risk factors of illness-related distress and defensive coping; and (c) increase outcomes of self-transcendence and resilience. Methods A multi-site, randomized controlled trial (COG-ANUR0631) conducted at 8 Children’s Oncology Group sites involving 113 AYA aged 11–24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase’s Resilience in Illness Model. Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning and resilience at baseline (T1), post-intervention (T2), and 100-days post-transplant (T3). Results At T2, the TMV group reported significantly better courageous coping (ES=0.505; P=0.030). At T3, the TMV group reported significantly better social integration (ES=0.543; P=.028) and family environment (ES=0.663; P=0.008), as well as moderate non-significant effect sizes for spiritual perspective (E=0.450; P=0.071) and self-transcendence (ES=0.424; P=0.088). Conclusion The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high risk cancer treatment. We recommend the TMV be examined in a broader population of AYA with high risk cancers.

Effectiveness of Music Therapy on Social Skill Growth in Educable Intellectual Disability Boys

“…So it is compatible with the results achieved in previous studies on the effect of music therapy in improving psychological function and resolve of some psychiatric disorders including anxiety and improve stress management [7] [10] [11] [16]- [20]. The effect music therapy on social growth may be due to mood regulation [6]- [8] or by improving function of brain in coping with stress, self-satisfaction and self-confidence increases [13]- [15]. As music induces safe environment for good social relationship, it may cause positive self-esteem and increases social approach and interests [16]- [19].…”

“…Some studies revealed that music has positive impact on human behaviors and mood [6]- [8]. Therefore music has been used for treatment of medical and psychiatric disorders [8] [9].…”

Psychosocial interventions for adolescents and young adult cancer patients: A systematic review and meta-analysis

“…A trend for an increased quality of life was observed in the intervention group. This feasibility study was the pilot for the study of Robb et al [44]. Here, the same study design was used to further investigate primary (e.g.…”

“…Six studies [39][40][41][42][43][44] examined the effects of technologybased interventions. The majority of these studies used multiple outcome parameters.…”

The effect of audio therapy to treat postoperative pain in children undergoing major surgery: a randomized controlled trial

“…Nevertheless, prior studies focused primarily in the use of music therapy to minimize pain associated with short medical procedures such as venipuncture but not for the treatment of post-surgical pain [9][10][11]. The distracting and anxiolytic properties of audiobooks may also have a promising effect on pain control in children undergoing surgery but their efficacy remains to be evaluated [12]. Currently, there is a lack of recommendation for non-pharmacological strategies by practice guidelines for the treatment of post-surgical pain in children [13].…”