Randomized clinical trial of the influence of local water-filtered infrared A irradiation on wound healing after abdominal surgery

Abstract

Postoperative irradiation with wIRA can improve normal postoperative wound healing and may reduce costs in gastrointestinal surgery.

Water-filtered infrared A reduces chlamydial infectivity in vitro without causing ex vivo eye damage in pig and mouse models

“…It is known that wIRA has a thermal component (18,20,37), which prompted us to examine temperature during 30 min Similar results were obtained in the cell culture experiments. Even though the initial intra-well temperature was slightly higher with wIRA alone, there was no significant difference amongst the filters after the irradiation period of 30 min.…”

“…Surprisingly, the number of chlamydial inclusions was also reduced following irradiation of uninfected HCjE alone without any direct treatment of Chlamydia leading us to hypothesize that a wIRA-induced cellular protective effect is stimulated against subsequent chlamydial infection. According to several other studies, this might be due to an increased cell metabolism (16)(17)(18)(19). Knels et al recently discovered that wIRA irradiation of fibroblast cultures not only enhances metabolic activity, but also that it has a protective effect on cells, improving their viability under oxidative stress.…”

“…Water-filtered infrared A radiation (wIRA) with a radiation spectrum ranging from 780 to 1400 nm has been used successfully, either alone or in combination with visible light (VIS), to aid the healing process of acute and chronic wounds, improving tissue oxygen partial pressure and perfusion, as well as reducing pain, inflammation and the frequency of wound infection (16)(17)(18)(19) .…”

Wassergefiltertes Infrarot A (wIRA) hilft Wunden heilen

“…Der Median der Schmerzminderung an den postoperativen Tagen 2 bis 6 betrug 13,4 auf einer visuellen 100-mm-Analogskala (VAS 0-100). Der Schmerz in der Kontrollgruppe blieb dagegen unverändert (p<0,000001) [2,3,6,7]. Der Median der Schmerzminderung am 3. postoperativen Tag betrug 18,5 gegenüber 0,0, die mediane Differenz zwischen den Gruppen 18,4 (99%-Konfidenzintervall, 99%-KI, 12,3/21,0, p<0,000001) [2,3,6,7].…”

“…Die erforderliche Analgetikadosis war in den Untergruppen mit wIRA(+VIS) 52-69% niedriger (mediane Differenzen) im Vergleich zu den Kontrolluntergruppen mit nur VIS (Median 598 gegenüber 1398 ml Ropivacain, p=0,000020, für Periduralkatheteranalgesie; 31 gegenüber 102 mg Piritramid, p=0,00037, für patientenkontrollierte Analgesie; 3,4 gegenüber 10,2 g Metamizol, p=0,0045, für i.v.-und orale Analgesie) [2,3,6,7].…”