Randomized clinical trial of enteral yeast‐selenium supplementation in preterm infants

G, Bogye; Alfthan, Georg; Machay, T

doi:10.1002/biof.5520080123

Cited by 10 publications

(8 citation statements)

References 10 publications

(11 reference statements)

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“…Intravenous selenium administration improves the outcomes for preterm infants born in selenium-deficient areas [69,70]. Placebo controlled clinical trials also increase the fertility of men living in low selenium areas leading to successful conception [71].…”

Section: Clinical Studies With Dietary Seleniummentioning

confidence: 99%

Dietary selenium and selenoprotein function

2012

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SummarySelenium is a trace mineral and an essential nutrient in the human diet. Selenium is found in soil and water and consequently enters the food chain through the root ways of plants and aquatic organisms. Some areas of the world are low in soil selenium resulting in a selenium deficient population and the appearance of an associated heart disease and bone disorders that can be corrected with dietary selenium. Indeed the requirement for dietary selenium was established by these observations and while selenium deficiency is rare in the West, patients requiring long-term intravenous feedings have also show heart disease associated with a deficiency of selenium in the feeding fluids. Subsequently, it has been established that dietary selenium can improve a wide range of human health conditions even in areas with soil replete in selenium.

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Section: Clinical Studies With Dietary Seleniummentioning

confidence: 99%

Dietary selenium and selenoprotein function

2012

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“…Makhoul et al ( 8 ) and Lockitch et al ( 21 ) observed that the lower the weight, the lower the concentration of selenium in newborns. Bogye, Alfthan and Machay ( 38 ) stated that very low birth weight premature infants are obviously susceptible to selenium deficiency.…”

Section: Discussionmentioning

confidence: 99%

“…Surveys claim that selenium concentrations are lower in preterm infants, especially in those with low birth weight (Ë‚1,500 g) and very low birth weight (Ë‚1,000g), when compared with term infants ( 22 , 37 , 38 , 45 , 46 ) .…”

Section: Discussionmentioning

confidence: 99%

“…Makhoul et al ( 8 ) e Lockitch et al ( 21 ) observaram que, quanto mais baixo o peso, menor a concentração de Se nos recém-nascidos. Bogye et al ( 38 ) afirmaram que prematuros com peso muito baixo ao nascer são obviamente suscetíveis à deficiência de Se.…”

Section: Discussionunclassified

“…Pesquisas afirmam que as concentrações de Se são mais baixas em lactentes prematuros, especialmente naqueles com baixo peso ao nascer (Ë‚1500g) e peso muito baixo ao nascer (Ë‚1000g), quando comparados com crianças nascidas a termo ( 22 , 37 , 38 , 45 , 46 ) . Daniels et al ( 18 ) , ao estudarem prematuros recebendo NP, encontraram níveis de Se semelhantes aos observados em crianças com a doença de Keshan.…”

Section: Discussionunclassified

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Selenium deficiency and the effects of supplementation on preterm infants

Freitas

Nogueira

Antônio

et al. 2014

Rev. paul. pediatr.

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Objective: This study aimed to review the literature about blood concentrations of selenium associated with gestational age, feeding, supplementation and related clinical features in preterm infants. Data sources: Systematic review in the following databases: MEDLINE, PubMed, Google academics, SciELO. org, ScienceDirect (Elsevier) and CINAHL-Plus with Full Text (EBSCO). Articles published up to January 2013 with the keywords "selenium deficiency", "selenium supplementation", "neonates", "infants", "newborn" and "preterm infants" were selected. Data synthesis: The studies reported that low blood selenium levels are associated with increased risk of respiratory diseases. Preterm infants, especially with low birth weight, presented lower selenium levels. Selenium deficiency has also been associated with the use of oral infant formula, enteral and parenteral nutrition (with or without selenium addition). The optimal dose and length of selenium supplementation is not well-established, since they are based only on age group and selenium ingestion by breastfed children. Furthermore, the clinical status of the infant affected by conditions that may increase oxidative stress, and consequently, selenium requirements is not taken into account. Conclusions: Prematurity and low birth weight can contribute to low blood selenium in premature infants. Selenium supplementation seems to minimize or prevent clinical complications caused by prematurity.

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