Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme

King, PM; Blazeby, Jane M; Ewings, Paul; Franks, Peter J.; Longman, RJ; Kendrick, Adrian; Kipling, RM; Kennedy, R. H.

doi:10.1002/bjs.5216

Cited by 327 publications

(364 citation statements)

References 25 publications

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“…A minority of these fasttrack protocols include the use of laxatives, mostly magnesia, an osmotic agent without colon-stimulating properties [7,9,43,44]. The inclusion of a colonstimulating laxative in rehabilitation programs may confer additional benefit by decreasing the duration of colonic hypomotility.…”

Section: Discussionmentioning

confidence: 99%

Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial

Zingg

Mišković

Pasternak

et al. 2008

Int J Colorectal Dis

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Section: Discussionmentioning

confidence: 99%

Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial

Zingg

Mišković

Pasternak

et al. 2008

Int J Colorectal Dis

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“…King and colleagues examined information regarding inpatient days, out-patient and general practitioner visits and the use of community services and estimated costs from national published figures. 84 Direct medical and indirect non-medical costs were significantly lower in the ERAS group. Similarly, Sammour and colleagues have recently published a cost-analysis of ERAS in colorectal surgery.…”

Section: Health Economic Benefitsmentioning

confidence: 91%

Enhanced recovery after surgery (ERAS) protocols: Time to change practice?

Melnyk

Casey

Black

et al. 2013

CUAJ

262

120

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Radical cystectomy with pelvic lymph node dissection remains the standard treatment for patients with muscle invasive bladder cancer. Despite improvements in surgical technique, anesthesia and perioperative care, radical cystectomy is still associated with greater morbidity and prolonged in-patient stay after surgery than other urological procedures. Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery. The key elements of ERAS protocols include preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens and early mobilization. Despite the significant body of evidence indicating that ERAS protocols lead to improved outcomes, they challenge traditional surgical doctrine, and as a result their implementation has been slow.The present article discusses particular aspects of ERAS protocols which represent fundamental shifts in surgical practice, including perioperative nutrition, management of postoperative ileus and the use of mechanical bowel preparation.

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“…Although conventional multiport laparoscopic colectomy (MLC) is less invasive than open colectomy (OC) and results in less postoperative pain [50][51][52], it still requires several Excluding three studies [23,30,33] which did not exactly report on the mean number of harvested LN incisions for port placement as well as a specimen extraction site, many of which are sited separately on the abdominal wall [52][53][54]. Only five studies [55][56][57][58][59] reported less postoperative pain after ML-RH than after O-RH, with the difference being statistically significant in three [55,57,58] of them.…”

Section: Discussionmentioning

confidence: 99%

Single-Incision Laparoscopic Right Hemi-Colectomy: a Systematic Review

Αποστόλου

Orfanos²,

Papalois

et al. 2015

Indian J Surg

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As surgeons became more adept with laparoscopic colon surgery, other less invasive procedures, such as singleincision laparoscopic right hemi-colectomy (SIL-RH), have been applied. The objective of this study was to evaluate the safety of SIL-RH as well as its intraoperative and postoperative outcomes for right-sided colon diseases. A detailed search in PubMed for citations that included SIL-RH from 2000 to 2014 revealed 21 studies fulfilling the criteria of the present review. A total of 684 patients were analyzed. Of the patients, 50.2 % were men. Mean patient age was 64.8 years. Of the patients, 36.1 % had already undergone an abdominal operation before the performance of SIL-RH, while 69 % of the patients underwent SIL-RH for colon cancer. Relatively low rates of overall morbidity (15 %) and mortality (0.75 %) were reported in the included studies. Mean length of postoperative hospital stay (LOS) was 5.5 days. Bowel motility return had a mean value of 2.8 days. Mean number of harvested lymph nodes (LN) was 19.2 LN. All resection margins were tumorfree. SIL-RH was a safe alternative to multiport laparoscopic right hemi-colectomy (ML-RH) in terms of morbidity and mortality, postoperative gastrointestinal function recovery, LOS, as well as oncological radicalness.

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Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme

Cited by 327 publications

References 25 publications

Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial

Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial

Enhanced recovery after surgery (ERAS) protocols: Time to change practice?

Single-Incision Laparoscopic Right Hemi-Colectomy: a Systematic Review

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