Randomized clinical trial comparing helmet continuous positive airway pressure (hCPAP) to facemask continuous positive airway pressure (fCPAP) for the treatment of acute respiratory failure in the emergency department

Adi, Osman; Via, Gabriele; Salleh, Siti Hafsah; Chuan, Tan Wan; Rahman, Jamalludin Ab; Muhammad, Nik Azlan Nik; Atan, Rafidah; Yunos, Nor’azim Mohd

doi:10.1016/j.ajem.2021.06.031

Cited by 9 publications

(4 citation statements)

References 38 publications

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“…Der Einsatz des Helmes ging mit einer höheren Toleranz der Patienten, einer geringeren Komplikationsrate hinsichtlich Hautverletzungen, Augenirritationen und Magenüberblähung und einer Reduktion der Intubationsrate und der Letalität einher [439,440]. Adi und Mitarbeiter konnten in einer randomisierten Studie bei hypoxämischen Patienten in der Notaufnahme eine geringere Intubationsrate feststellen, wenn ein Helm als Interface benutzt wurde [441]. Eine im Jahr 2017 publizierte Metaanalyse attestiert der Helm-NIV im Vergleich zur Masken-NIV eine niedrigere Intubationsrate, eine kürzere Dauer der Intensivbehandlung sowie eine geringere in Hospital und 90-Tage-Mortalität [442].…”

Section: Beatmungszugang (Interface)unclassified

S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz

Westhoff,

Neumann,

Geiseler

et al. 2023

Pneumologie

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ZusammenfassungDie Leitlinienaktualisierung zeigt die Vorteile sowie die Grenzen der NIV bei der Behandlung von akutem Atemversagen im klinischen Alltag und bei unterschiedlichen Indikationen auf.Die nichtinvasive Beatmung (NIV) hat einen hohen Stellenwert bei der Therapie des hyperkapnischen akuten Atemversagens, da sie die Aufenthaltsdauer und den Krankenhausaufenthalt auf der Intensivstation sowie die Mortalität deutlich reduziert.Patienten mit kardiopulmonalem Ödem und akutem Atemversagen sollten zusätzlich zu notwendigen kardiologischen Eingriffen mit kontinuierlichem positivem Atemwegsdruck (CPAP) und Sauerstoff behandelt werden. Dies sollte bereits präklinisch und in der Notaufnahme erfolgen.Bei anderen Formen des akuten hypoxämischen Atemversagens mit nur leicht bis mäßig gestörtem Gasaustausch (PaO2/FiO2 > 150 mmHg) ergibt sich kein signifikanter Vor- oder Nachteil gegenüber nasaler Sauerstoff-High-Flow-Therapie (HFNO). Bei schweren Formen des ARDS ist die NIV mit einer hohen Rate an Behandlungsversagen und Mortalität verbunden, insbesondere in Fällen mit NIV-Versagen und verzögerter Intubation.Zur Präoxygenierung vor der Intubation sollte NIV verwendet werden. Bei Risikopatienten wird eine NIV empfohlen, um Extubationsversagen zu reduzieren. Im Entwöhnungsprozess von der invasiven Beatmung reduziert NIV das Risiko einer Reintubation bei hyperkapnischen Patienten wesentlich. NIV gilt in der Palliativversorgung als nützlich zur Reduzierung von Dyspnoe und zur Verbesserung der Lebensqualität, hier aber in Konkurrenz zur HFNO, das als komfortabler gilt. Mittlerweile wird die NIV auch im präklinischen Bereich empfohlen, insbesondere bei hyperkapnischem Atemversagen und beim Lungenödem.Bei entsprechender Überwachung auf einer Intensivstation kann NIV auch bei pädiatrischen Patienten mit akuter Ateminsuffizienz erfolgreich eingesetzt werden.

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Section: Beatmungszugang (Interface)unclassified

S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz

Westhoff,

Neumann,

Geiseler

et al. 2023

Pneumologie

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“…d) In patients presenting to the ED with acute cardiogenic pulmonary edema or decompensated COPD, hCPAP was non-inferior to fCPAP and resulted in greater comfort levels and lower intubation rate [37].…”

Section: Relative To Psychological Therapies In Patientsmentioning

confidence: 99%

“…This study adds to the knowledge of conceptual innovations in primary care to support patients with COPD and CHF. Adi O, et al [37] Helmet continuous positive airway pressure (hCPAP) to facemask continuous positive airway pressure (fCPAP) for the treatment of acute respiratory failure in the emergency department R: 113…”

Section: Kitzman Dw Et Al [213]mentioning

confidence: 99%

Heart Failure (HF): Recent innovations in clinical therapy and critical profiles of acute and chronic forms

Perrotta¹

2022

J Cardiovasc Med Cardiol

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Background and objectives: Heart failure is a pathological condition characterized by the inability of the heart to pump (cardiac output) an adequate amount of blood to meet the metabolic needs of the body or, at any rate, to be able to do so only at the expense of increased filling pressures in one or more cardiac chambers and the upstream venous circulation. The research group states here the primary objective of expanding the indications contained in the ESC 2021 with the results of the last year on the subject of treatment profiles, to facilitate a better understanding of the overall clinical picture and contribute to the next edition of the guidelines. Materials and methods: Systematic literature review in the English language from January 1, 2021, to September 30, 2022, on PubMed/MedLine, Web on Science, and Cochrane archive. Our search strategy retrieved 8,317 articles. We excluded books and papers, meta-analyses, reviews, and systematic reviews and selected only 46 studies most significant about the clinical trial and randomized controlled trial. Results: The recent ESC 2021 guidelines are accurate and timely, and have confirmed their usefulness from a functional perspective, including concerning certain aspects that were represented as a “grey area”. Early risk prediction plays a key role in the subsequent management of patients, and to optimize risk prediction and intensity of management, one should take into account that: a) biomarkers have improved the understanding of the pathophysiology of heart failure and may therefore help to adjust the intensity of management in AHF; b) among the wide variety of biomarkers currently available, NT-proBNP and cTn seem the most promising in this indication; c) among the risk scores described, those combining demographic and clinical parameters with biomarkers in a model with routinely available rapid variables seem the most promising tools; d) in addition to biomarkers, age, systolic blood pressure, respiratory rate, oxygen saturation, creatinine, electrolytes, and blood urea nitrogen are the most commonly used predictor variables in the risk scores described; e) among the models selected, the MEESSI-AHF risk score appears to be currently the most promising tool for predicting the risk of AHF; f) during the management of decompensated patients (and in later stages), the psychological aspect is completely ignored, thus promoting the worsening of psychological symptoms (the need is as evident during the acute episode as it is in the daily management of chronic heart failure). Conclusions: The scientific literature search enriched the structure of ESC 2021, suggesting its implementation, with other findings related to new drug therapies such as Sotagliflozin, Hydrochlorothiazide Apabetalone, Alprostadil, Empagliflozin, Sacubitril/Valsartan, Dapagliflozin, Sodium-glucose co-transporter-2 inhibitors, and biomarkers such as Urinary sodium (UNa+), IL-6 levels and rh-brain natriuretic peptide (rhBNP), as well as the use of mindful breathing session, osteopathic manipulative treatment, electrical muscle stimulation, low-level tragus stimulation, venoarterial extracorporeal membrane oxygenation, oral nutritional supplements, and the correlative hypothesis between heart failure and intestinal dysbiosis, also concerning the psychological profile. However, these clinical studies suffer from some limitations that will necessarily have to be taken into account, such as the limited size of the population sample selected or the conflict of interest determined by the fact that some research is funded by the same pharmaceutical company producing the drug used that do not necessarily represent a negative limitation on the results obtained from studies.

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“…Inserting a nasogastric tube may be relatively difficult when using FMV, which could impact the intraoperative need for gastric emptying. Implementing positive end-expiratory pressure (PEEP) during FMV may also be relatively challenging, and PEEP may be necessary for certain patients, such as those with acute respiratory distress syndrome (ARDS) [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of trans-nasal humidified rapid insufflation ventilatory exchange compared with standard facemask oxygenation for pre- and apneic oxygenation during anesthesia induction: A meta-analysis based on randomized controlled trials

Zheng,

Yao,

Luo

et al. 2024

PLoS ONE

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Purpose To further identify the effectiveness of trans-nasal humidified rapid insufflation ventilatory exchange (THRIVE) for pre- and apneic oxygenation during the anesthesia induction by comparison to facemask ventilation (FMV) based on current available evidence. Methods Medline, EMBASE, Web of Science, Cochrane Library and CNKI databases were searched from inception to December 22, 2023 for available randomized controlled trials (RCTs). Primary outcomes were PaO2 and PaCO2 after intubation and safe apnoea time. Secondary outcomes included the O2 desaturation, end expiratory carbon dioxide (EtCO2) and complications. The effect measures for continuous and categorical outcomes were separately the mean difference (MD) and relative risk (RR) with 95% confidence interval. Results Twelve RCTs with 403 patients in the THRIVE group and 401 patients in th FMV group were included. Pooled results demonstrated that the PaO2 after intubation was significantly higher (MD = 82.90mmHg, 95% CI: 12.25~153.54mmHg, P = 0.02) and safe apnoea time (MD = 103.81s, 95% CI: 42.07~165.56s, P = 0.001) was longer in the THRIVE group. Besides, the incidence rate of O2 desaturation (RR = 0.28, 95% CI: 0.12–0.66, P = 0.004) and gastric insufflation (RR = 0.26, 95% CI: 0.13–0.49, P<0.001) was significantly lower in the THRIVE group. Conclusion Based on current evidence, THRIVE manifested better effectiveness representing as improved oxygenation, prolonged safe apnoea time and decreased risk of complications compared to standard FMV in surgical patients. Therefore, THRIVE could be served as a novel and valuable oxygenation technology for patients during anesthesia induction.

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Randomized clinical trial comparing helmet continuous positive airway pressure (hCPAP) to facemask continuous positive airway pressure (fCPAP) for the treatment of acute respiratory failure in the emergency department

Cited by 9 publications

References 38 publications

S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz

S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz

Heart Failure (HF): Recent innovations in clinical therapy and critical profiles of acute and chronic forms

Effectiveness of trans-nasal humidified rapid insufflation ventilatory exchange compared with standard facemask oxygenation for pre- and apneic oxygenation during anesthesia induction: A meta-analysis based on randomized controlled trials

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