1981
DOI: 10.1007/bf00200315
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Randomized clinical study on intratumoral BCG-cell wall preparation (CWP) therapy in patients with squamous cell carcinoma in the head and neck region

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Cited by 19 publications
(3 citation statements)
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References 41 publications
(39 reference statements)
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“…Later, accumulating pre-clinical evidence supported the use of BCG for cancer therapy (16). Clinicians reported the therapeutic benefits of intra-tumoral injections of BCG in several types of cancers such as melanoma (1720) or squamous cell carcinoma of the head and neck (21). MD Anderson hospital reported up to 2500 patients with all types of cancer treated with BCG, including scarification of the tumors (22).…”
Section: Introductionmentioning
confidence: 99%
“…Later, accumulating pre-clinical evidence supported the use of BCG for cancer therapy (16). Clinicians reported the therapeutic benefits of intra-tumoral injections of BCG in several types of cancers such as melanoma (1720) or squamous cell carcinoma of the head and neck (21). MD Anderson hospital reported up to 2500 patients with all types of cancer treated with BCG, including scarification of the tumors (22).…”
Section: Introductionmentioning
confidence: 99%
“…In the last two decades immunotherapy with Bacillus Calmette-Gu6rin (BCG) has been widely studied in experimental animal tumour systems [3,27], in spontaneously occurring tumours in pet [30] and farm animals [18,23,24] and in tumours in man [4,15,40]. In horses intralesional immunotherapy with BCG was used by Wyman et al [47] and Murphy et al [29] for the treatment of sarcoid skin tumours in 2 and 7 horses respectively.…”
Section: Introductionmentioning
confidence: 99%
“…When the dosage of BCG increased to 5 mg/ml, a marked increase of NK cell activity was demonstrated Discussion BCG is a nonspecific biological response modifier and has been used systemically as an immunotherapeutic agent in many malignant diseases without satisfactory results [19]. However, it did have favorable responses in treating certain malignancies such as melanoma [20], squamous cell carcinoma of head and neck [21 ], and blad der tumor [22][23][24][25]. Intravesical instillation of BCG for Table 1.…”
Section: Resultsmentioning
confidence: 99%