The value distribution of derivatives of characteristic polynomials of matrices from SO(N ) is calculated at the point 1, the symmetry point on the unit circle of the eigenvalues of these matrices. We consider subsets of matrices from SO(N ) that are constrained to have n eigenvalues equal to 1, and investigate the first non-zero derivative of the characteristic polynomial at that point. The connection between the values of random matrix characteristic polynomials and values of L-functions in families has been well-established. The motivation for this work is the expectation that through this connection with L-functions derived from families of elliptic curves, and using the Birch and Swinnerton-Dyer conjecture to relate values of the L-functions to the rank of elliptic curves, random matrix theory will be useful in probing important questions concerning these ranks.