It has been found in scientific papers devoted to the search for new QTL and deciphering their significance and contribution to real indicators in cattle that these loci are most often breed-specific. Detailed research of the molecular genetic characteristics of each breed is an important tool for breeding and improving the efficiency of breeding farms. From the point of view of the choice of the object of study, Kazakh White-headed and Auliekol breeds are of considerable interest, since being related breeds bred for a long time in the same climatic territory, each of them is a carrier of unique productive traits. The purpose of the research was to search for SNP complexes for QTL marking of meat productivity in cattle of Auliekol and Kazakh White-headed breeds of Kazakh breeding based on data from genome-wide DNA typing. The results of SNP typing of cattle of Kazakh White-headed and Auliekol breeds using GeneSeek GGP Bovine 150K biochip with an average coverage density of 150,000 SNP (Illumina Inc., USA) have been presented the article. The genome-wide association study (GWAS) was performed using Plink, a set of genome-wide association analysis tools designed to perform a number of basic large-scale analyses. Sixty seven significant SNPs associated with traits of growth were found. Eight of these SNPs belong to Auliekol breed, 59 to Kazakh White-headed breed. For Auliekol breed significant associations were found for the indicators of live weight at birth, at weaning and live weight of one-year-old bulls (the threshold of significance for all traits was 0.001). In Kazakh White-headed breed was found associations with the live weight at birth, at weaning, as well as the average daily gain of live weight in bulls.