Ramsay-Hunt syndrome complicated by unilateral multiple cranial nerve palsies

Herpes Zoster Laryngitis Accompanied by Ramsay Hunt Syndrome

“…It is important to differentiate herpes zoster laryngitis from other diseases to make a correct diagnosis. 1,2,6,8 Herpes zoster laryngitis sometimes presents with unilateral laryngeal edema and vocal fold paralysis, suggesting a laryngeal tumor, laryngeal tuberculosis, fungal infection, syphilis, abscess, or nonspecific laryngeal inflammation, thus making a differential diagnosis necessary. 1,8 Moreover, in the case of unilaterally widespread cranial nerve involvement, malignant infiltration or sarcoidosis should be excluded.…”

“…1,8 Moreover, in the case of unilaterally widespread cranial nerve involvement, malignant infiltration or sarcoidosis should be excluded. 2,9 Therefore, physical examination, laboratory tests, including routine blood test, serologic test for VZV, and cerebrospinal fluid study, and radiologic examinations are needed. 1,2,9 Tissue biopsy and virus culture can also be performed but are rarely used in clinical practice.…”

“…2,9 Therefore, physical examination, laboratory tests, including routine blood test, serologic test for VZV, and cerebrospinal fluid study, and radiologic examinations are needed. 1,2,9 Tissue biopsy and virus culture can also be performed but are rarely used in clinical practice. 6 Antiviral therapy with acyclovir has been shown to be effective in VZV infection.…”

Herpetic inflammation of multiple cranial nerves

“…We read with great interest the paper of Morelli et al [1] which described a patient with varicella-zoster reactivation from multiple unilateral cranial ganglia and/or nerves. This report is quite interesting as, to the best of our knowledge, such extensive involvement of cranial nerves V, VII, VIII, IX, X, XI and XII has not been previously reported.…”

Ramsay Hunt Syndrome with multiple cranial nerve palsy

“…But because of its close relationship with VIII nerve and its ganglions as it travels through the internal auditory canal and inner ear; infection may spread to the VIII nerve and presentation with sensory neural hearing loss or dizziness is not unusual. But other cranial nerve involvement is rare [2][3][4] .…”