Raman spectroscopy as a tool for monitoring osteoporosis therapy in postmenopausal osteoporosis
J. Renwick Beattie,
Mark R. Towler
Abstract:Bisphosphonate‐based pharmacological therapy of osteoporosis reduces risk of fracture, but modulation of bone mineral density does not solely explain this. Additional bone quality aspects affecting fragility need to be better understood, alongside methods to monitor them. Systemic factors that influence bone collagen remodelling also remodel keratin in parallel processes. In this study, human fingernail clippings from subjects with and without bone active pharmaceutical intervention are compared. A discriminan… Show more
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