Raman spectroscopy analysis of new copper‐cysteamine photosensitizer

Abstract

Raman spectroscopy and several microstructure analysis techniques have been used to better characterize recently synthesized copper‐cysteamine Cu3Cl(SR)2, where R = CH2CH2NH2. Nanoparticles of this new copper‐cysteamine have been identified as having potential applications in radiation detection and cancer treatment because of the fact that they can be activated by light, X‐rays, ultrasound, and microwave radiation to produce reactive oxygen species. Three samples were grown under different conditions, and their microstructure was examined by using Raman spectroscopy, Fourier transform infrared, scanning electron microscopy, energy dispersive X‐ray scattering, and X‐ray diffraction. The Raman spectroscopy and Fourier transform infrared measurements identify numerous Raman active and infrared absorption bonds with wavenumbers ranging from 200 to 3,500 cm−1. Scanning electron microscopy scans show well‐faceted crystals varying in size from approximately 10 nm to 4 μm, energy dispersive X‐ray scattering measurements identify relative elemental composition (C = 48%, N = 37.5%, S = 5%, Cl = 2.6%, Cu = 7%), X‐ray diffraction data show the crystal plane spacing varies from 0.8454 to 0.8616 nm. The microstructure observed for the three samples is consistent with variations in the growth conditions.

Copper-Cysteamine Nanoparticles as a Heterogeneous Fenton-Like Catalyst for Highly Selective Cancer Treatment

“…We further measured the FTIR spectra and XRD patterns of Cu-Cy before and after the Fenton-like reaction (Figure C and D). As shown in Figure C, the FTIR spectra of Cu-Cy matched with previously reported results . The peaks at 3300 cm –1 , 2800 cm –1 , and 1600 cm –1 correspond to NH 2 stretching, CH 2 stretching, and N–H bending, respectively.…”

“…As shown in Figure 3C, the FTIR spectra of Cu-Cy matched with previously reported results. 47 The peaks at 3300 cm −1 , 2800 cm −1 , and 1600 cm −1 correspond to NH 2 stretching, CH 2 stretching, and N−H bending, respectively. Additionally, the peaks that are in the range of 700−1300 cm −1 correspond to C−N and C−C−N vibrations.…”

Recent advances in linear and nonlinear Raman spectroscopy. Part XIV

“…Akafzade et al [ 92 ] reported Raman spectral analysis from nanoparticles of a new copper‐cysteamine photosensitizer. These nanoparticles have been identified as having potential applications in radiation detection and cancer treatment because of the fact that they can be activated by light, X‐rays, ultrasound, and microwave radiation to produce reactive oxygen species.…”

Progress of Raman spectroscopic investigations on the structure and properties of coal

“…Raman spectroscopy is a type of molecular vibrational spectroscopy based on the Raman scattering effect. It has the advantages of simple sample preparation, in situ analysis, and nondestructive treatment of samples and has been widely used in geology, [37,38] material, [39,40] environmental, [41][42][43][44][45] and other fields. [46] Raman spectroscopy gives detailed information on the chemical structure and crystallinity of carbonaceous materials.…”