Raised inflammatory markers

Pretreatment elevated erythrocyte sedimentation rate and C-reactive protein as a predictor of malarial complications

“…CRP and amyloid A are very early markers of inflammatory responses [20]. In addition to elevated CRP in bacterial infections, higher levels have also been seen in parasitic disease [22]. Previous studies observed higher levels of pro-inflammatory mediators in severe malaria and improvement in level markers following recovery from severe malaria, but the role of pro-inflammatory mediators in predicting these complications has not been studied [6].…”

“…Measurement of amyloid A is not done in routine practice. The availability of CRP and ESR measurement at point of care [22] makes them ideal markers for identifying complications at an early stage of malaria and offers an additional advantage for prognostication at the primary care level.…”

Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: a large case–control study using electronic records

“…12 Early diagnosis of myeloma in primary care should be possible in theory: plasma viscosity (or other inflammatory markers), serum protein, and protein electrophoresis are generally available. 13 However, initiating investigation requires recognition of the possibility of myeloma.…”

Quality Process Measures for Rheumatoid Arthritis: Performance from Members Enrolled in a National Health Plan

“…Elevations in ESR and CRP levels are an effective marker for inflammation, although their usefulness in tracking inflammation levels in individuals with chronic inflammation such as RA remains unclear. 23 Discordant results have been reported among the 2 tests, and baseline levels can change with age. [24][25][26] Further, the correlation of ESR and CRP levels with disease activity is not straightforward.…”