RAFT preparation and the aqueous self-assembly of amphiphilic poly(octadecyl acrylate)- block -poly(polyethylene glycol methyl ether acrylate) copolymers

Chong, Josephine; Keddie, Daniel J.; Postma, Almar; Mulet, Xavier; Boyd, Ben J.; Drummond, Calum J.

doi:10.1016/j.colsurfa.2015.01.047

Cited by 20 publications

(21 citation statements)

References 100 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…40 RAFT polymerisation of LA in toluene gave poly(lauryl acrylate) (P[LA]) with a range of targeted degrees of polymerisation (DP n = 25, 50 and 100, M n,th = 6,000 -24,000 g mol -1…”

Section: Resultsmentioning

confidence: 99%

Functionalisation of MWCNTs with poly(lauryl acrylate) polymerised by Cu(0)-mediated and RAFT methods

et al. 2016

Self Cite

View full text Add to dashboard Cite

Permanent WRAP URL:http://wrap.warwick.ac.uk/79040 Copyright and reuse:The Warwick Research Archive Portal (WRAP) makes this work of researchers of the University of Warwick available open access under the following conditions. Copyright © and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and practicable the material made available in WRAP has been checked for eligibility before being made available.Copies of full items can be used for personal research or study, educational, or not-for-profit purposes without prior permission or charge. Provided that the authors, title and full bibliographic details are credited, a hyperlink and/or URL is given for the original metadata page and the content is not changed in any way. Publisher statement:First published by Royal Society of Chemistry 2016 http://dx.doi.org/10.1039/C6PY00522E A note on versions:The version presented here may differ from the published version or, version of record, if you wish to cite this item you are advised to consult the publisher's version. Please see the 'permanent WRAP URL' above for details on accessing the published version and note that access may require a subscription. Poly (

show abstract

“…40 RAFT polymerisation of LA in toluene gave poly(lauryl acrylate) (P[LA]) with a range of targeted degrees of polymerisation (DP n = 25, 50 and 100, M n,th = 6,000 -24,000 g mol -1…”

Section: Resultsmentioning

confidence: 99%

Functionalisation of MWCNTs with poly(lauryl acrylate) polymerised by Cu(0)-mediated and RAFT methods

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…This value was slightly lower than that of homopolymer of PEGMA, namely, PPEGMA ( M n of PEGMA = 480; M n = 10,906; CMC = approximately 700 mg·L −1 ) reported by Hussain et al These values are quite large, more than 20‐fold greater than that of PSt 30 ‐ b ‐PPEGA 200 . As an amphiphilic block copolymer having PPEGA as a hydrophilic segment, Chong et al reported that the CMC value of poly(octadecyl acrylate) 10 ‐ b ‐PPEGA 34 (PC18A 10 ‐ b ‐PPEGA 34 ) was 3.7 mg·L −1 , which was slightly lower than that of PSt 30 ‐ b ‐PPEGA 34 (CMC = 6.2 mg·L −1 ) . The calculated M n value of the PC18A 10 segment (3240) was close to that of PSt 30 (3120).…”

Section: Resultsmentioning

confidence: 80%

RAFT synthesis of polystyrene‐block‐poly(polyethylene glycol monomethyl ether acrylate) for zinc phthalocyanine‐loaded polymeric micelles as photodynamic therapy photosensitizers

Obata

Tanaka

Mizukoshi

et al. 2017

J. Polym. Sci. Part A: Polym. Chem.

View full text Add to dashboard Cite

A series of polystyrene‐block‐poly(polyethylene glycol monomethyl ether acrylate) (PStm‐b‐PPEGAn) polymers were systematically synthesized as carriers for zinc phthalocyanine (ZnPc) for photodynamic therapy via reversible addition and fragmentation chain transfer polymerization. The degree of polymerization of the styrene (m) and PEGA units (n) of the resulting block copolymers were characterized to be n = 174, 40, and 18 for m = 52; and n = 200, 84, and 31 for m = 30. All the block copolymers formed micelles in water. The critical micelle concentration (CMC) of the PStm‐b‐PPEGAn was determined by fluorometry using pyrene as a hydrophobic probe. The CMC value increased from 4.5 to 20 mg·L−1 with an increase in the mole fraction of PEGA units. The median diameters of the micelles increased from 19 to 31 nm for PSt52‐b‐PPEGAn and from 15 to 23 nm for PSt30‐b‐PPEGAn with increasing n value. ZnPc‐loaded micelles were prepared by dialysis of the block copolymer in the presence of ZnPc followed by removal of large aggregates by filtration. The encapsulation efficiency was dramatically changed in the range of 0–68%. The light‐dose‐dependent cytotoxicity of the ZnPc‐loaded PSt30‐b‐PPEGA200 was clearly established in HeLa cell lines; while no cytotoxicity was confirmed under the dark. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 560–570

show abstract

“…The polymeric chain bending forms aggregates frequently named flower‐like structures. [ 2,4,31,52,53 ] Copolymers with a PMMA central block (Figure 8) assume the inversed bent conformation to build the core–shell structure. These copolymers presented narrow size particle distributions with diameters ranging from 350 to 1000 nm Additionally, for the copolymer P (SMA 3 ‐ b ‐MMA 896 ‐ b ‐SMA 3 ), it is possible to observe a less intense peak in Figure 8b, ranging from 10 to 30 nm, suggesting the presence of folded unimers.…”

Section: Resultsmentioning

confidence: 99%

“…Amphiphilic block copolymers have been extensively studied due to their special features and wide range of possible applications such as rheological modifiers agents, [ 1 ] drug and gene delivering systems, [ 2 ] nanoelectronics and nano‐optics, energy‐efficient bottom‐up structuring of bulk materials, [ 3 ] and so on. One of the most notable features of amphiphilic block copolymers is the capability to self‐assemble in solid state and in solution.…”

Section: Introductionmentioning

confidence: 99%

Triblock Copolymers Based on Sucrose Methacrylate and Methyl Methacrylate: RAFT Polymerization and Self‐Assembly

Marcilli

Petzhold

Felisberti

2020

Macro Chemistry & Physics

View full text Add to dashboard Cite

delivering systems, [2] nanoelectronics and nano-optics, energy-efficient bottom-up structuring of bulk materials, [3] and so on. One of the most notable features of amphiphilic block copolymers is the capability to self-assemble in solid state and in solution. This behavior results from the different chemical characteristics and solubility of the blocks, which are typically immiscible and soluble in different solvents. [4] The morphology of structures built from copolymer self-assembly is directly correlated with the copolymer structure, composition, and molar mass and demands synthetic strategies that provide accurate control over the polymerization. [4] In this context, controlled radical polymerization (CRP) [5][6][7] or reversible-deactivation radical polymerization (RDRP), [8] a more accurate denomination for specific cases such as for the reversible additionfragmentation chain transfer (RAFT) poly merization, plays an important role. RAFT has attracted a lot of interest from researchers in the last twenty years due to its versatility to synthesize copolymers with controlled molar mass, architecture, and narrow molar mass dispersity (Đ M ). [9] (Co)polymerization in sequential steps by RAFT is an efficient strategy to synthesize amphiphilic block copolymers, as reported elsewhere. [9][10][11][12] Sequential multistep polymerization allows designing the architecture of multiblock copolymers with different properties depending on the mono mer characteristics and the addition sequence. Another important issue with RAFT polymerization is the chain transfer agent (CTA), which determines polymerization control and, mainly, the architecture of copolymer (star-like copolymers, symmetric and nonsymmetric polymeric chains, and so on). Keddie et al. [6] and Moad et al. [9] published a very broad and in-depth discussion about RAFT polymerization of different monomers and CTA and their special features and applications. The information in these works facilitates the rational choice of CTA for certain monomers and desired polymer architectures.ABA and BAB triblock amphiphilic copolymers based on sucrose methacrylate and methyl methacrylate are synthesized by sequential reversible additionfragmentation chain transfer polymerization using S,S′-bis(R,R′-dimethyl-R′′-acetic acid)-trithiocarbonate as a chain transfer agent. The copolymers present narrow molar mass dispersity, controlled molar mass and architecture as determined by gel permeation chromatography and 1 H and 13 C nuclear magnetic resonance. The copolymers with molar and mass fractions of poly(sucrose methacrylate) block ranging from 1 to 22 mol% and 3 to 52 wt%, respectively, and different molar masses present characteristics of a surfactant such as self-assembly. The self-assembly of the triblock copolymers in water, N,N-dimethylformamide (DMF), dichloromethane, tetrahydrofuran, or benzene results mostly in vesicles as confirmed by scanning electron microscopy images and small-angle X-ray of the dispersions. Moreover, the copolymers present the capability to st...

show abstract

RAFT preparation and the aqueous self-assembly of amphiphilic poly(octadecyl acrylate)- block -poly(polyethylene glycol methyl ether acrylate) copolymers

Cited by 20 publications

References 100 publications

Functionalisation of MWCNTs with poly(lauryl acrylate) polymerised by Cu(0)-mediated and RAFT methods

Functionalisation of MWCNTs with poly(lauryl acrylate) polymerised by Cu(0)-mediated and RAFT methods

RAFT synthesis of polystyrene‐block‐poly(polyethylene glycol monomethyl ether acrylate) for zinc phthalocyanine‐loaded polymeric micelles as photodynamic therapy photosensitizers

Triblock Copolymers Based on Sucrose Methacrylate and Methyl Methacrylate: RAFT Polymerization and Self‐Assembly

Contact Info

Product

Resources

About